Mica: An integrated web platform to support epidemiological studies

Etienne Morency (emorency@p3g.org)

Mica

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What is Mica ? Mica infrastructure (Maelstrom repository) Step 1: Mica Catalogues Step 2: Mica Variables Step 3: Processing, Integration and

Dissemination Conclusion

Mica

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Software Infrastructure Mealstrom-Research

Web portal to document studies that are using our harmonization tools

Operational IT infrastructure that supports management of individual harmonization projects Integrated – Series of interrelated software (ONYX, OPAL, MICA,

DataSHIELD and DataSHaPER). Solid “communication routes” with other resources (PhenX, Molgenis, DDI):

Comprehensive – Support all steps of the harmonization process from study description to database federation and statistical analysis

Open source – Based on state-of-the-art and widely used open source frameworks, highly customizable and secure, freely available.

Toolkit to build websites for a study or a consortium Easy to install, to manage and extremely customizable

(based on Drupal and PHP)

Mica

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Architecture 3 architectures that links to the central

repository (all share core information)

Maelstrom-Research

Hosted

Network

Independent

Mica

1. Identifying and cataloguing participating studies

Mica

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Study Catalogue Mica

2. Identifying variables for harmonization

Mica

3. Data processing, integration and dissemination

Mica

Dataschema

Study A

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UK Biobank50,000 participants

Kora-gen1800participants

LifeGene50,000participants

HarmonizedDataset

HarmonizedDataset

Mica

Mica

Integration with Opal

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Conclusion Other Features

Role-based access control (files, fields, content types) Dissemination of Publications/Events/Projects/News And many other extensions (calendar, publication

workflow…) Updates

Ongoing development Catalogues (Questionnaires, Access, Biosamples

Physical Measures) / Follow-up Continue the integration with existing tools Implement the central repository: Maelstrom-

Research Translations support

Mica