Lichen Amyloidosis-2 - DermpathMD.comdermpathmd.com/cases/slide atlas/Lichen...

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Transcript of Lichen Amyloidosis-2 - DermpathMD.comdermpathmd.com/cases/slide atlas/Lichen...

What  is  the  best  diagnosis?  A.  Lichen  amyloidosis  B.  Macular  amyloidosis  C.  Acral  fibrokeratoma  D.  Glomus  tumor  E.  Nevus  sebaceus  

Lichen  amyloidosis  

Pearls    Irregular  epidermal  hyperplasia  with  hyper-­‐  and  parakeratotic  scale  

  Dermal  papillary  fibroplasia  with  hyaline  deposits  

 May  have  scattered  melanophages  

  Amyloid  stains  (eg  Congo  red)  may  not  be  positive  in  cutaneous  keratin-­‐derived  amyloid