Motore Siringa

3 ml

Motore Siringa

10 ml

Motore Siringa

5 ml

Carrello scorrevole

Punto

prelievo

Calibratore

di dosi

Experiences on various automatic dispenser for [Experiences on various automatic dispenser for [1818F]-FDG.F]-FDG.

AimAimOptimization of dispensing procedures of 18F-FDG to decrease absorbed doses by operators.Optimization of dispensing procedures of 18F-FDG to decrease absorbed doses by operators.

Introduction Our nuclear medicine department has begun the PET activity in 2002. Our nuclear medicine department has begun the PET activity in 2002.

Injectable doses were prepared manually and directly from the main vial, so operators were getting Injectable doses were prepared manually and directly from the main vial, so operators were getting high absorbed doses and nearly reached the limit.high absorbed doses and nearly reached the limit.

That’s why we had the urgency of an automatic dispensing systemThat’s why we had the urgency of an automatic dispensing system..

DDS-A system (TEMA Sinergie)DDS-A system (TEMA Sinergie)

Period of utilization: September 2003-Period of utilization: September 2003-October 2006October 2006

Problems related to DDS-A were due to several pump Problems related to DDS-A were due to several pump failures,with consequential errors in doses preparations.failures,with consequential errors in doses preparations.

Due to that, operators were exposed to unnecessary Due to that, operators were exposed to unnecessary extra doses while trying to reinitialize the entire process.extra doses while trying to reinitialize the entire process.

Fisiologica

Vial Radiofarmaco

Waste

Pannello in alluminio

Pompa peristaltica

18F-FDG Out

Waste

RP 300 Dispenser (MASPRES)RP 300 Dispenser (MASPRES)

Period of utilization Period of utilization : October 2006- November : October 2006- November 20082008

Problems related to this model were related to:Problems related to this model were related to:

Lack of an automatic diluition option for both single Lack of an automatic diluition option for both single doses and vialsdoses and vials

Impossibility to make vials with a volume greater then Impossibility to make vials with a volume greater then 20 ml20 ml

RP 300+ Dispensing unit (MASPRES)RP 300+ Dispensing unit (MASPRES)

Period of utilization: Sill in use since Period of utilization: Sill in use since November 2008November 2008

Differences between this model and the former one (RP 300), Differences between this model and the former one (RP 300), consist mainly in adding a second withdrawal exit (for the consist mainly in adding a second withdrawal exit (for the physiological solution) and a larger accomodation, suitable for physiological solution) and a larger accomodation, suitable for 30 ml vials. Gestional software has been updated with the 30 ml vials. Gestional software has been updated with the automatic dilution for both vials and syringes. Moreover,a automatic dilution for both vials and syringes. Moreover,a new dose calibrator has been installed inside the manipulating new dose calibrator has been installed inside the manipulating cell to allow a direct check on dispensed activity.cell to allow a direct check on dispensed activity.

Motore Siringa 3 ml

Motore Siringa 5 ml

Motore Siringa 10 ml

Carrello scorrevole

Punti di prelievo Alloggio

vial da 30 ml

Soluzione Fisiologica Radiofarmaco

Calibratore

di dosi

Results and ConclusionsResults and Conclusions

Using the first automated system (DDS-A), doses absorbed to hands by Using the first automated system (DDS-A), doses absorbed to hands by operators were lowered roughly by 50% (compared to manual operations)operators were lowered roughly by 50% (compared to manual operations)

Using the RP300 Dispensing system,that value has been lowered by Using the RP300 Dispensing system,that value has been lowered by another 30%another 30%

Clips

fissaggio

E-mail: sperandeo@lamaddalenanet.it

D. Busetta1; A. Cistaro2; A. Sperandeo1; N. Paligoric1; R. Mangiapane1; U. Ficola1.

1.O.U Nuclear Medicine Oncologic Dept, La Maddalena Hospital, Palermo, Italy2. Positron Emission Tomography Center IRMET S.p.A., Torino, Italy

Anyway,due to the problems listed Anyway,due to the problems listed above, there was still the necessity above, there was still the necessity of corrective actions on those of corrective actions on those devices, that were exposing devices, that were exposing operators to extra absorbed doses.operators to extra absorbed doses.

Using the upgaded version of RP Using the upgaded version of RP 300 (RP 300+ System), has been 300 (RP 300+ System), has been noted a further reduction on noted a further reduction on absorbed doses.absorbed doses.

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2000

4000

6000

8000

10000

12000

uS

v/m

ese

2003 2004 2005 2006 2007 2008

Procedura Manuale

Dispensatore DDS-A system (TEMA Sinergie)

Dispensatore RP 300 (MASPRESS)

Fisiologica