Ebola

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Ebola outbreak instigates all scientists and researchers to make a detailed study and provide some solutions for the discovery of a cure for human welfare. This presentation is such an attempt trying to make a difference in the research and development of Ebola virus disease

Transcript of Ebola

Herbal cure

for

Ebola virus disease (EVD)

Presented by Dr. Sudhakar KokateDirector PPRC, India

Dedicated

to

Ebola affected patients

all over the world

PPRC/INDIA 01

What is Virus?

A small infectious agent that replicates only inside

the living cells of other organisms

Infect all types of living forms

Also known as Virions

Of different shapes, size 1/100th of average bacterium

PPRC/INDIA 02

What is Virus?

They are made up of:

1. DNA/RNA, long molecules carrying genetic

information

2. Protein

3. An envelope of lipids

PPRC/INDIA 03

Important viral diseases

PPRC/INDIA 04

Influenza Small pox Hepatitis

Hepatic cirrhosis Kaposi sarcoma AIDS

Measles Pneumonia Bronchitis

Common cold Rabies Chickenpox

Herpes zoster EVD Viral meningitis

Ebola virus (EBOV)

Most dangerous of the known viruses

Named as Ebola in earlier Zaire (2010)

Family – Filoviridae

Species – Zaire ebolavirus

PPRC/INDIA 05

Ebola virus disease (EVD)

Severe disease, fatality rate upto 90%

Primarily in villages of Central-West Africa

Human to human transmission

First appeared in 1976 in Nizara, Sudan and

Yambuku

PPRC/INDIA 06

Symptoms of EVD

Sudden onset of fever

Intense weakness

Muscle pain

Headache

Sore throatPPRC/INDIA 07

Symptoms of EVD

Impaired liver and kidney function

Internal and external bleeding in some cases

Vomiting

Diarrhoea

RashPPRC/INDIA 08

Facts of Ebola

Formerly known as Ebola haemorrhagic fever

Ebola is caused by an RNA virus

Incubation period 2 -21 days

Bleeding is common in later stages

PPRC/INDIA 09

Types of tests

Antibody: capture enzyme linked immunosorbent

assay (ELISA)

Antigen detection tests

Serum neutralization tests

PPRC/INDIA 10

Types of tests

Reverse transcriptase polymerase chain reaction

(RT-PCR) assay

Electron microscopy

Virus isolation by cell culture

PPRC/INDIA 11

Ebola virus disease outbreak

PPRC/INDIA 12

Year Country Cases Deaths% case fatality

1976 Congo 318 280 88

1976 Sudan 284 151 53

1977 Congo 1 1 100

Ebola virus disease outbreak

PPRC/INDIA 13

1979 Sudan 34 22 69

1994 Gabon - Zaire 52 31 60

1995 Congo - Zaire 315 254 81

1996 Gabon - Zaire 31 21 68

Ebola virus disease outbreak

PPRC/INDIA 14

2000 Uganda Sudan 425 224 53

2001-2 Gabon - Zaire 65 53 82

2003 Congo - Zaire 202 172 82.2

2005 Congo - Zaire 12 10 83

Ebola virus disease outbreak

PPRC/INDIA 15

2007 Congo - Zaire 264 187 71

2008 Congo - Zaire 32 14 44

2012 Uganda Sudan 24 17 71

2012 Congo - Zaire 57 29 51

Types of tests

Reverse transcriptase polymerase chain reaction

(RT-PCR) assay

Electron microscopy

Virus isolation by cell culture

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WHO report

There is no cure for

Ebola Virus Disease (EVD)

No licensed vaccine

No specific treatment available

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Research work

All over the world

Many scientists, research groups are engaged in R&D

about development of drugs, vaccines against Ebola

and other diseases

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U.S. Defense Dept.

spent $140 mn on

Ebola virus disease treatment

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National Agency for food, drug &

control …. Scientific committee

(NAFDAC) claimed in 2013

effective herbs for Ebola virus and othersPPRC/INDIA 20

Azadirachta indica - Neem

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Allium sativum - Garlic

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Aloe barbadensis – Aloe vera

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Amaranthus yoruba: Green Amaranth

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Carica papaya - Papaya

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Cymbopogum citratus: Lemon grass

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Dioscorea alata – Water yam

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Euphoria hirta – Asthma plant

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Garcinia kola – Bitter kola

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Momordica charantia –Bitter melon

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Psidium guajava - Guava

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Sesamum indicum – Sesame

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Saccharum officinarum - Sugarcane

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Vernonia amygdalina – Bitter leaf

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Zea mays - Maize

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Attention!All Global scientists!!

I suggest following two plants for Ebola :

Tulsi, Ocimum sanctum

Indian curry leaf tree, Murraya koenigii

Do reciprocate: director.pprc@gmail.com

From,

Director, PPRCPPRC/INDIA 36

Ocimum sanctum - Tulsi

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Murraya koenigii – Indian curry leaf tree

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Thank You !!

“BE WITH US”