Dr Nikunj Bhatt. First line Defense: Epidermis Mucus Membranes Mucus Hairs Cilia Lacrimal...

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Transcript of Dr Nikunj Bhatt. First line Defense: Epidermis Mucus Membranes Mucus Hairs Cilia Lacrimal...

Dr Nikunj Bhatt

Dr Nikunj Bhatt

Dr Nikunj Bhatt

Dr Nikunj Bhatt

Dr Nikunj Bhatt

Dr Nikunj Bhatt

First line Defense:EpidermisMucus MembranesMucusHairsCiliaLacrimal appartuslysosome

Saliva Flow of Urine Vagina Secretion Defecation Vomiting Sebum Perspiration Gastric Juice

Dr Nikunj Bhatt

Second line Defense:Antimicrobial Protein

In Blood and Interstitial fluids

WBCs secretesInterferon Stops replication They are α, β ,Y

typesCompliment System promotes

Phagocytosis

TransferrinReduce Iron to inhibit growth of bacteria

Dr Nikunj Bhatt

Natural Killer cells and phagocytosis:5-10 % are NK [natural Killer] next to first line and Antimicrobial proteinNeutrophils and Macrophages: are two major Phagocytes has five phases

Chemotaxis Adherence Ingestion Digestion Killing

Dr Nikunj Bhatt

Inflammation: Tissue damage Redness,pain,hea

t and swelling

Dr Nikunj Bhatt

Maturation of t cells

Dr Nikunj Bhatt

Maturation of B cells

Dr Nikunj Bhatt

Antigen Immunogenicity Reactivity

Receptors epitope

Dr Nikunj Bhatt

APCs [Antigen Presenting Cells]

Dr Nikunj Bhatt

Activation Proliferation and Differentiation of T cells

Dr Nikunj Bhatt

Activation Proliferation and Differentiation of B cells

Dr Nikunj Bhatt

Dr Nikunj Bhatt

Dr Nikunj Bhatt