Danish National Peritonitis Survey

Post on 02-Jul-2015

187 views 1 download

Transcript of Danish National Peritonitis Survey

Danish National Peritonitis Survey

James Heaf for the Danish Society of Nephrology National Registry, Herlev Hospital, University of Copenhagen

This Power Point presentation belongs to the Danish Renal Registry, which owns the copyright. It can be freely used for non-commercial study and educational purposes. Any commercial use or publication requires the prior permission of the Danish Renal Registry.

P a t i e n t S u r v i v a l i n P e r i t o n e a l D i a l y s i s 1 9 9 0 - 2 0 0 6

9 0 - 9 5 9 5 - 0 0 2 0 0 0 -0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0 3 , 5 4 , 0

Y e a r s

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

P D T e c h n i q u e S u r v i v a l 1 9 9 0 - 2 0 0 6

9 0 - 9 5 9 5 - 0 0 2 0 0 0 -0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0 3 , 5 4 , 0

Y e a r s

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

T e m p o r a r y s w i t c h e s t o H D e x c l u d e d

P D T e c h n i q u e a n d P a t i e n t S u r v i v a l

9 0 - 9 5 9 5 - 0 0 2 0 0 0 -0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0 3 , 5 4 , 0

Y e a r s

0 , 1

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

What happens to PD Patients?

HD 38%

Transplant 34%

Death 28%

1990-2005

0

10

20

30

40

50

60

%/Y

ear

2000 2001 2002 2003 2004 2005 All

Year

Peritonitis Incidence 2000-2005

Peritonitis by Center 2000-5

0 20 40 60 80

RigshospitalHerlev

HillerødRoskildeHolbæk

Nykøbing FOdense

SønderborgEsbjerg

FredericiaHolsterbro

SkejbyViborg

Aalborg

%/Year

a

b

a: 2002-5b: 2001-5

L a s t P e r i t o n i t i s b e f o r e P D C e s s a t i o n

T e m p o r a r y H D

P e r m a n e n t H D0 1 2 3 4 5 6

T i m e b e f o r e P D C e s s a t i o n ( m o n t h s )

0 , 6 0

0 , 6 5

0 , 7 0

0 , 7 5

0 , 8 0

0 , 8 5

0 , 9 0

0 , 9 5

1 , 0 0

Cum

ulat

ive

Pro

port

ion

Sur

vivi

ng

D e a t h

3% of all PD patients diein relation to peritonitis.8% of all PD patients change permanently to HD in relationto peritonitis.

T i m e t o 1 s t , 2 n d a n d 3 r d P e r i t o n i t i s

0 1 2 3 4

Y e a r s

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cum

ulat

ive

Pro

port

ion

Sur

vivi

ng

First

Second

Third

T i m e b e t w e e n P e r i t o n i t i s E p i s o d e s

0 , 0 0 , 5 1 , 0 1 , 5 2 , 0 2 , 5 3 , 0

S u r v i v a l T i m e ( y e a r s )

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

T i m e t o 1 s t p e r i t o n i t i s

1 s t t o 2 n d P e r i t o n i t i s

2 n d t o 3 r d P e r i t o n i t i s

Peritonitis Frequency/YearA l l P D C o u r s e s

0

0 - 0 , 5

0 , 5 - 1

1 - 2

2 - 3

> 3

P D C o u r s e s > 1 y e a r

0

0 - 0 , 5

0 , 5 - 1

1 - 2

2 - 3

P D C o u r s e s > 2 y e a r s

0

2 - 3

1 - 2

0 , 5 - 1

0 - 0 , 5

P D C o u r s e s > 3 Y e a r s

0

2 - 31 - 2

0 , 5 - 1

0 - 0 , 5

APD vs. CAPD

0

10

20

30

40

50

60

70

%/Year

CAPD APD

56

43

N o E f f e c t o f R e n a l D i a g n o s i s o nP e r i t o n i t i s - f r e e S u r v i v a l

S m a l l G N C I N P o l y c y s t i c D i a b e t i c H y p e r t e n s i v e O t h e r0 , 0 0 , 5 1 , 0 1 , 5 2 , 0

Y e a r s

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

N o E f f e c t o f S e x o n P e r i t o n i t i s - f r e eS u r v i v a l

M a l e F e m a l e0 1 2 3 4

Y e a r s

0 , 0

0 , 1

0 , 2

0 , 3

0 , 4

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

E f f e c t o f A g e o n P e r i t o n i t i s - f r e e S u r v i v a l

< 3 0 3 0 - 4 0 4 0 - 5 0 5 0 - 6 0 6 0 - 7 0 > 7 00 , 0 0 , 5 1 , 0 1 , 5 2 , 0

T i m e

0 , 5

0 , 6

0 , 7

0 , 8

0 , 9

1 , 0

Cu

mu

lativ

e P

rop

ort

ion

Su

rviv

ing

p < 0 . 0 5