Cytokines and endothelial adhesion molecules (sVCAM-1)

in preeclampsia

Cytokines and endothelial adhesion molecules (sVCAM-1)

in preeclampsia

INTRODUCTION INTRODUCTION

INTRODUCTION INTRODUCTION

INTRODUCTION INTRODUCTION

The aim of the present work was to study the charac-teristics of the production of

proinflammatory and anti- inflammatory cytokines, vascular endothelial adhesion

molecule-1 (sVCAM-1) as markers of endothelial dys-function and their interactions, with varying

degrees of severity of preeclampsia.

MATHERIALS AND METHODS MATHERIALS AND METHODS

MATHERIALS AND METHODS MATHERIALS AND METHODS

MATHERIALS AND METHODS MATHERIALS AND METHODS

MATHERIALS AND METHODS MATHERIALS AND METHODS

MATHERIALS AND METHODS MATHERIALS AND METHODS

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

The content of IL-1β IL-4, IL-6, IL-8, IL-10, G-GSF, TGF-β2 and sVCAM-1 in the blood serum of

pregnant surveyed groups (M ± m).

The content of IL-1β IL-4, IL-6, IL-8, IL-10, G-GSF, TGF-β2 and sVCAM-1 in the blood serum of

pregnant surveyed groups (M ± m).

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

RESULTS AND DISCUSSION RESULTS AND DISCUSSION

a significant decrease in concen-trations TGF-β2 and IL-10 in severe preeclampsia was indicated,

which may testify the exhaustion of adaptive mechanisms

CONCLUSIONCONCLUSION

• In the pathogenesis of preeclampsia signifi-cant role plays development of the process of immune inflammation in the complex with endothelial dysfunction.

• These processes are shown enhanced expression of intercellular adhesion molecule and activation of the immune response in their relationship, growing to a se-vere disease process.

• In the pathogenesis of preeclampsia signifi-cant role plays development of the process of immune inflammation in the complex with endothelial dysfunction.

• These processes are shown enhanced expression of intercellular adhesion molecule and activation of the immune response in their relationship, growing to a se-vere disease process.

CONCLUSIONCONCLUSION

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