Post on 23-Jun-2020
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♣ 1. Introductory Data:
Position: Prof. of Biochemistry/Molecular Biology, Faculty of Science,
Cairo University.
Date of Birth: 25/3/1965
Gender: Female
Nationality: Egyptian
Marital Status: Married.
Home Address: El Feda Compound - villa 36, 6th of October City, Egypt.
Cell phone:
E-mail: mervat_sayed@yahoo.com
mervat@sci.cu.edu.eg
♣ 2. Employment History:
☻ Employer: Chemistry Department, Biochemistry Unit, Faculty of Science,
Cairo University and Al-Ain University – UAE.
Position
From : To
1- Prof. of Biochemistry / Molecular biology June 2013- Present
2- Associate Prof. of Biochemistry/ Molecular
biology
(2007 – 2013)
Curriculum Vitae
Mervat Sayed Mohamed
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3- Lecturer of Biochemistry/ Molecular
biology
(2001 - 2007)
4- Assistant Lecturer of Biochemistry- at Al-Ain
University- UAE.
( 1996-2001 )
4- Assistant Lecturer of Biochemistry/
Molecular biology
(1991 – 1996)
5- Instructor of Biochemistry (1986 – 1991)
♣ 3. Educational Qualification:
College/ University Degree Grade
Date
Faculty of Science /
Cairo University.
Ph.D in Biochemistry without 1995
Ph.D Thesis Title:
“Lactoferrin in neutrophil polymorphonuclear leucocytes in
leukaemias ; Biochemical & cytochemical study’’
Faculty of Science /
Cairo University.
M.Sc in biochemistry without 1991
M.Sc Thesis Title: “ Biochemical studies in bilharzial infected mice”
♣ 4. Research Experience:
☻ I have been supervising on many M.Sc and Ph.D theses (nearly 20) in the
fields of Biochemistry , Molecular biology and Biotechnology.
♣ 5. Teaching Experience:
Course No. of Times Level
Proteomic & functional
genomics . 4 Ph.D Biochemistry Students
Cancer Biology 4 M.Sc Students
3
Recent advances in
biotechnology ( industrial
biotechnology/enzyme
engineering )
4 Ph.D Biochemistry Students
DNA technology 10 M.Sc Biochemistry Students
Molecular biology
( gene cloning and
molecular tools)
20
Undergraduate For
1- Biotechnology students
2- Biochemistry students
Tissue Culture 6 M.Sc Biochemistry students
Carbohydrate Metabolism 10
Undergraduate For
1-Biology students
2-Biochemistry students
3- Biotechnology students
Lipid and protein
metabolism 10
Undergraduate For
1- Biology students
2- Biochemistry students
Body fluids 10 Undergraduate For
Biochemistry students
Structure of Biomolecules 8 Undergraduate For
Biochemistry students
Clinical Biochemistry 8
Undergraduate For
1- Biology students
2- Biochemistry students
Vitamins 2 Undergraduate For
Biochemistry students
Practical courses in
molecular biology and
biochemistry
27 years Undergraduates
♣ 6. Laboratory Skills and Techniques:
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siRNA synthesis & Maldi -tof mass spectral.
Molecular Biology: Gene Cloning expression and purification which
includes:
Isolation of Total RNA.
RT-PCR by using gene specific Primer.
Purification of PCR Product.
Gene cloning.
Vector transformation into Bacterial cells.
Induction by IPTG, followed by SDS-PAGE to confirm the
expression.
Detection of expressed protein by Western blot technique.
PCR: Primer Designing for PCR.
Protein purification: Purification of recombinant protein
Electrophoresis Techniques: Electrophoresis of DNA/RNA on Agarose
gel and electrophoresis of protein on SDS-PAGE.
Microbiological Techniques:
Competent cell preparation.
Transformation and preparation of culture media.
Biochemical Techniques:
Estimation of concentration of DNA, RNA, Protein and
enzymes.
Chromatography techniques, Paper, Column and HPLC.
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Immunological techniques: Immunocytochemistry and ELISA.
Microscopic technique: Confocal Microscopy.
Computer Skills:
Microsoft Office.
Primer designing.
Gene sequence analysis.
Retrieval of data from various databases.
Gene Scan and protein databases.
Phylogenetic tree.
Gel Documentation Program.
♣ 7. Management Experience:
Member of the editorial/advisory board of the Current World
Environment (CWE) journal published by Oriental Scientific Publishing
Company, Asia ISSN, 0973-4929.
Coordinator of biotechnology program (special program at Faculty of
Science, Cairo University, 2008 -2009). My main role was developing the
program protocol and following up its progress. The program ranked first
in the Quality Assurance and Accreditation Center in Egypt.
Coordinator of Ph.D program of Biochemistry, Cairo University, Faculty of
Science (2010 - present).
♣ 8. Scientific Consultation:
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Organization Name Type of Consultation Period of
Consultation
Cairo University Supervisor of Central Lab 2006-2009
Cairo University Development of biotechnology
curriculum
2008-2009
♣ 9. Training Experience:
Training attended Place Date
Oligonucleotide synthesis and its
usage as RNA antisense
Ulm University, Ulm, Germany 2004
A contributor in the workshop of
DNA technology
Cairo University 2005
Two months workshop in Protein
Crystallization and Drug Design
Cairo University 2006
Two months training in
bioinformatics
Sira, Egypt 2007
♣ 10. Conferences:
A- International:
Conference Name Topic Date and Place Type of participation
3rd
conference of
Synchrotron
Azurin as
Antitumor Protein
and its Effect on the
Cancer Cell Lines
2007, Jordan Project Poster
B- Local:
Conference Name Topic Date and Place Type of participation
5th
International
Conference of
Chemistry
Degradation of
methomyl by the
novel bacterial strain
Stenotrophomonas
maltophilia M1
2010, Egypt Speaker
4th
conference of 4th
conference of 2008, Egypt Poster
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Synchrotron Synchrotron
4th
international
conference of
Chemistry
Isolation and
characterization of
novel bacterial
strain from
Egyptian lakes
capable of
degrading the
widely used
pesticide, methomyl
2006, Egypt Speaker
53rd
conference of
Laboratory
Medicine
Prophylactic and
curative effect of
zingiber officinale
against
hyperlipaemia in
albino rats.
2005, Egypt
Poster
♣ 11. Projects:
Title of research Year Fund and Participation
“Screening for Novel Pesticides
Degrading Bacteria, Cloning, and
Molecular Characterisation of
Gene(s) Involved in Pesticides
degradation”
2007 Funded by Cairo University
♣ 12. International Journals (with high impact factors):
Author at:
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Clinica Chimica Acta.
Clinical Biochemistry.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.
Australasian Plant Pathology.
Electronic Journal of Biotechnology.
African Journal of Biotechnology.
Indian Journal of Clinical Biochemistry.
• Applied Biochemistry Biotechnology.
Journal of Genetic Engineering and Biotechnology
Mermber at :
Middle East Molecular Biology Society
♣ 13. List of Publications:
1. Mohamed A. Ragheb, Mohamed A. Eldesouki, Mervat S. Mohamed : DNA
binding, photo-induced DNA cleavage and cytotoxicity studies of lomefloxacin
and its transition metal complexes (2015). Spectrochimica Acta Part A:
Molecular and Biomolecular Spectroscopy . 138 ; 585–595.
2. Magda F. Mohamed, Mervat S. Mohamed, Mohamed M. Fathib, Samia A.
Shoumanc and Ismail Abdelshafy Abdelhamid (2014). Chalcones Incorporated
Pyrazole Ring Inhibit Proliferation, Cell Cycle Progression,Angiogenesis and
Induce Apoptosis of MCF7 Cell Line. Anti-Cancer Agents in Medicinal
Chemistry. 14; 1282-1292.
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3- T. A. A. Moussa1, M. S. Mohamed and N. Samak . Production and
characterization of Di-Rhamnolipid produced by Pseudomonas aeruginosa
TMN ( 2014 ) . Brazilian Journal of Chemical Engineering. 31(4) ; 867 – 880.
4. Emad F Eskander, Ahmed A Abd-Rabou, Mervat S. Mohamed, Shaymaa
MM Yahya, Ashraf El Sherbini, Olfat G Shaker ( 2014 ) : The Potential Impact
of P53 and APO-1 Genetic Polymorphisms on Hepatitis C Genotype 4a
Susceptibility. Gene. 15; 550(1):40-5.
5. Emad F. Eskander, Ahmed A. Abd-Rabou, Shaymaa M. M. Yahya, Ashraf El
Sherbini, Mervat S. Mohamed , Olfat G. Shaker ( 2014 ) : The Impact of
Pegylated-Interferon-α plus Ribavirin on Prolactinemia and Testosteronemia
among Hepatitis C-Genotype-4a Patients , Open Journal of Biochemistry: 2 (1)
: 1-8.
6. Emad F. Eskander , Ahmed A. Abd-Rabou , , Shaymaa M. M. Yahya ,
Mervat S. Mohamed ,Olfat G. Shaker ( 2014 ): P53 Codon 72 Single Base
Substitution in Viral Hepatitis C and Hepatocarcinoma Incidences . Indian
Journal of Clinical Biochemistry: 29 (1): 3-7
7- Mohamed A. 1 Eldesouki, Nevin E. Sharaf, Alia A. Abdel Shakour,
Mervat S. Mohamed, Amal S. Hussein and Ibrahim W. Hasani ( 2013): Study
of the Effect of Occupational Exposure to Volatile Organic Compounds
(VOC’s) on Male Reproductive Hormones. World Journal of Medical Sciences
8 (1): 06-12.
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8- Emad F. Eskander, Ahmed A. Abd-Rabou, Shaymaa M. M. Yahya, Ashraf
El Sherbini, Mervat S. Mohamed, Olfat G. Shaker ( 2013 ): Correlation and
Multiple Regression Analyses of Pituitary Growth Hormone and Hepatic
Activities in Hepatitis C Infection and Interferon Response. Indian Journal of
Clinical Biochemistry . 28(4): 348-357.
9. Magda F. Mohamed , Mervat S. Mohamed , Samia A. Shouman , Mohamed
M. Fathi &Ismail Abdelshafy Abdelhamid ( 2012 ): Synthesis and Biological
Evaluation of a Novel Series of Chalcones Incorporated Pyrazole Moiety as
Anticancer and Antimicrobial Agents. Appl Biochem Biotechnol , 168(5 )
: 1153-1162 .
10. Emad F. Eskander a, Ahmed A. Abd-Rabou , Shaymaa M.M. Yahya , Olfat
G. Shaker , Mervat S. Mohamed ( 2012 ): Does interferon and ribavirin
combination therapy ameliorate growth hormone deficiency in HCV genotype-
4 infected patients? Clinical Biochemistry ,45: 3–6
11. Nadia I. Zakhary, Mervat S. Mohamed, Ola Khorshid ,Remon S. Azer ,
Naglaa Zayed: (2012) . Role of glypican-3 in the early diagnosis of
hepatocellular carcinoma among Egyptian patients , Journal of Genetic
Engineering and Biotechnology ,10: 73–79.
12. Soliman A. M. , Amal A. Ahmed1 , Mervat S. Mohamed , Demiana H.
Hanna ; B. N. Barsoum (2012): Gazar virus Y, a new member of the celery
mosaic virus group of potyviruses, isolated from carrots in EGYPT:
Australasian Plant Pathology, 41 (5) : 529-534.
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13. Emad F. Eskander, Mervat S. Mohamed, Ahmed A. Abd-Rabou, Shaymaa
M. M. Yahyaa, Olfat G. Shaker (2012): Does HCV Patients Who Have BCL2
43Ala Genotype and Normal GH1 Levels Can Achieve Response to IFN Based
Therapy? Indian Journal of Clinical Biochemistry, 27(4) : 344-350.
14. Mervat S. Mohamed, Azza A. Shoukry, and Ayat G. Ali (2012) : Synthesis and
structural characterization of ternary Cu (II) complexes of glycine with 2,2′-
bipyridine and 2,2′-dipyridylamine. The DNA-binding studies and biological
activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 86:
562- 570 .
15.Azza A. Shoukry & Mervat S. Mohamed ( 2012 ) : DNA-binding,
Spectroscopic and antimicrobial studies of Palladium (II) complexes containing
2, 2΄-bipyridine and 1-phenylpiperazine : Spectrochimica Acta Part A: Molecular
and Biomolecular Spectroscopy , 96 : 586–593
16. Olfat G. Shaker , Emad F. Eskander , Shaymaa M.M. Yahya, Mervat S.
Mohamed and Ahmed A. Abd-Rabou (2011): Genetic variation in BCL-2 and
response to interferon in hepatitis C virus type 4 patients : Clinica Chimica Acta
, 412 : 593–598
17. Mervat S. Mohamed , Walid Abu El-Soud and Magda F. Mohamed
(2011): Cloning and expression of the recombinant NP24I protein from tomato
fruit and study of its antimicrobial activity : African Journal of Biotechnology,
10(65), 14276-14285
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18. Mervat S. Mohamed , Salwa F. Sabet , Mohamed M. Moustafa and
Mohamed S. Salama (2011) : Correlation between a single nucleotide
polymorphism (G/T at nt –88) in the Mx1 gene promoter and the response to
interferon therapy for hepatitis C virus in Egyptian patients : African Journal of
Biotechnology, 10(62): 13376-13382
19. Mervat S. Mohamed , Said A. Fattah and Howayada M. Mostafa (2010 ):
Azurin as Antitumor Protein and its Effect on the Cancer Cell Lines : Current
Research Journal of Biological Sciences.
20. Mervat S. Mohamed ( 2009) : Degradation of Methomyl by the Novel
Bacterial Strain Stenotrophomonas maltophilia M1 . Electronic Journal of
Biotechnology, 12 (4) .
21. Goda S. K., Mohamed M.S. and Rashedi F.B. (2007): Isolation and
structure determination of two naturally inhibitors for salivary alpha-amylase, a
possible role as hypoglycemic drugs. Arab J. Lab. Med., 33 (1): 83-92.
22. Mohammad A.M., Mohamed M.S., Attaby F.A. and Abo-Taleb H. (2007):
N-acetyl transferase 2 gene polymorphism in bladder cancer. Arab J. Lab.
Med., 33 (1) : 93-101.
23. Mervat S. Mohamed ; Ahmed S, Abd-Allah; Nagwa S, Abd-Allah,
Manal El-Deeb; Soad Sultan and Adel S, Mohamed. (2007): Role of Serum
Interleukin -6 and Osteocalcin in Prediction of Bone Loss in Postmenopausal
Women. Med.J.Cairo univ.,75(1) ,Suppl.March:117-121.
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24. Mervat S.Mohamed (2006): Isolation and characterization of novel
bacterial strain from Egyptian lakes capable of degrading the widely used
pesticide, methomyl. Biosciences, Biotechnology Research Asia , 3(1a): 17-22.
25. Said,M.M.; El Sayed, A.S. Mervat S. Mohamed and Maria , F.Elmhdwi.
(2006): Biochemical evaluation of Ginkgo biloba extract (EGB) in Albino
Rats. 53 rd
Sceintific Congress, International Meeting, Cairo, Egypt (accepted
for publication)
26. El-Kannishy S.M. , Mohamed M.E. , Abo Hashem E.M and Riad B.Y.
(2005): The state of plasma nitric oxide metabolites (N02- and N0 3
- ) and
endothelin-1 in patients with chronic renal failure and/or ischemic heart
disease. Arab J. Lab. Med. , 31 (1): 49-62.
27. Said, M. M.; El Sayed, A. S. ; Mohamed, M.E. and Maria, F.Elmhdwi.
(2005): Prophylactic and curative effect of zingiber officinale against
hyperlipaemia in albino rats. J.Drug Res. Egypt, 26 (1):28-37.
28. El-Kannishy S.M. , Mohamed M.E. , Abo Hashem E.M and Riad B.Y.
(2005): The state of the major circulating apolipoproteins in patients with
chronic renal failure and/or ischemic heart disease. Arab J. Lab. Med., 31 (1):
31-47.
29. Mervat S. Mohamed, A.E.Zakaria, B.Y.Riad and N.S.El-Gendy. (2005):
Isolation and characterization of potent biodesulfurizing microorganisms from
the Egyptian environment. Egypt.J.Biomed.Sci., 19 :305-315.
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30- El-Kannishy S.M. , Mohamed M.E. , Abo Hashem E.M and Riad B.Y.
(2005). Hyperhomocysteinemia in chronic renal failure is an evolving risk
factor for ischemic heart disease. Med.J.Cairo Univ. ,73 (1):163-170.
♣ 14. Manuscripts in preparation:
Mervat S. Mohamed: Production and Structural characterization of Di-
rhamnolipid produced by Pseudomonas aeruginosa TMN strain isolated from
Compost pile waste, Egypt
♣ 15. Language skills:
Arabic: Mother Tongue
English: Excellent in reading & writing. Very good in speaking
English: Excellent in speaking scientific language .
French: Fair
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