AlcoholsQ 0230 DOI: 10.1002/chin.201151054

Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation Using Unsym-metrical Vicinal Diamine-Based Ligands: Dramatic Substituent Effect on Cata-lyst Efficiency. — With the best ligand, excellent enantioselectivities that are compa-rable to N-tosyl-1,2-diphenylethane-1,2-diamine are achieved. It is found that changing the substituent on the carbon bearing the -NH2/NHTs group in the ligand leads to a dra-matic difference in catalyst reactivity and enantioselectivity. — (ZHANG, B.; WANG, H.; LIN*, G.-Q.; XU, M.-H.; Eur. J. Org. Chem. 2011, 22, 4205-4211, http://dx.doi.org/10.1002/ejoc.201100299 ; Shanghai Inst. Org. Chem., Chin. Acad. Sci., Shanghai 200032, Peop. Rep. China; Eng.) — Bartels

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