Post on 12-Jan-2016
Chapter 2
Neuroscience and Behavior
Neural Communication• Biological/neuroscience Psychology
–branch of psychology concerned with the links between biology and behavior
–Want a better understanding of sleep and dreams, depression and schizophrenia, hunger, sex, stress and disease
Neural Communication• Neuron
– a nerve cell– the basic building block of the nervous system
• Dendrite– the bushy, branching extensions of a neuron that
receive messages and conduct impulses toward the cell body
– Brings in info
• Axon– the extension of a neuron, ending in branching
terminal fibers, through which messages are sent to other neurons or to muscles or glands
• Myelin [MY-uh-lin] Sheath – a layer of fatty cells that encase the fibers of
many neurons– Speeds up neutral impulses– MS
Neural Communication• Action Potential
– a neural impulse; a brief electrical charge (Ion) that travels down an axon
– Outside the Axon= positive ions– Inside the Axon= negative ions– Even positive and negative= resting potential, which acts like a gate
.– Depolarization= unfreezes or ungates the axon allowing the
message to go through – Refractory period= resting period, when extra atoms are pushed out – Some signals excite and some inhibit
• Threshold – the level of stimulation required to trigger
a neural impulse
– All or nothing
Neural Network
Neural Communication• Synapse Synapse
– junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron
– tiny gap at this junction is called the synaptic gap or cleft• Neurotransmitters
– chemical messengers that cross the synaptic gaps between neurons
– Excite or inhibit – Lock and key– Reuptake
•
•
Neurotransmitters • Each pathway uses different neurotransmitters, each neurotransmitter has a
different function • Acetylcholine ( ACH)
- muscle contraction, learning and memory– Alzheimer's
• Endorphins- – “morphine within” – natural, opiatelike neurotransmitters– linked to pain control and to pleasure
• Dopamine- alertness and movement– Parkinson's– schizophrenia
Neurotransmitters• Serotonin- mood, hunger,sleep and arousal
• depression• Norepinephrine- controls alertness and arousal• Gamma-aminobutryic acid (GABA)- inhibitory
neurotransmitter • Glutamate- A major excitatory neruo., memory
– Migraines– Seizures
Dopamine pathways
How Drugs Effect Neurotransmitters
• Many drugs mimic the neurotransmitter–Agonists excite
–Antagonists inhibit
Neurotransmitter molecule
Receiving cellmembrane
Receptor site onreceiving neuron
Agonist mimicsneurotransmitter
Antagonistblocksneurotransmitter
The Nervous System
The Nervous System
Central(brain and
spinal cord)
Nervoussystem
Autonomic (controlsself-regulated action of
internal organs and glands)
Skeletal (controlsvoluntary movements of
skeletal muscles)
Sympathetic (arousing)
Parasympathetic (calming)
Peripheral
The Nervous System
• The Nervous System –Body’s communication system –2 parts- Central and Peripheral–The Nervous System uses 3 types of
neurons • 1. Sensory • 2. Interneurons• 3. Motor neurons
Central Nervous System
•
Peripheral Nervous System
•
A. Central nervous system B. Peripheral nervous systemB1. Somatic nervous systemB2. Autonomic nervous system 1. Cerebrum2. Brainstem3. Cerebellum4. Spinal cord
A. Central nervous system B. Peripheral nervous systemB1. Somatic nervous systemB2. Autonomic nervous system 1. Cerebrum2. Brainstem3. Cerebellum4. Spinal cord
A. Central nervous system B. Peripheral nervous systemB1. Somatic nervous systemB2. Autonomic nervous system 1. Cerebrum2. Brainstem3. Cerebellum4. Spinal cord
A. Central nervous system B. Peripheral nervous systemB1. Somatic nervous systemB2. Autonomic nervous system 1. Cerebrum2. Brainstem3. Cerebellum4. Spinal cord
The Peripheral System• 2 components
–1. Somatic Nervous SystemSomatic Nervous System- controls our skeletal muscles
–2.Autonomic Nervous SystemAutonomic Nervous System- glands,muscles of our internal organs
–Heartbeat, digestion, hormones –1. Sympathetic Nervous SystemSympathetic Nervous System- defense actions
( increases heartbeat, muscles contract…..)–2. ParasympatheticParasympathetic- it conserves energy
Central Nervous System ( CNS)
• Spinal Cord and Brain
• Spinal Cord connects peripheral system to the brain
• Reflexes
Skinreceptors
Muscle
Sensory neuron(incoming information)
Motor neuron(outgoing information)
Brain
Interneuron
Spinal cord
The Brain
Tools of Discovery • Manipulating the brain –
• Lesions• electromagnetic charges• chemical and magnetic stimulation
• Clinical Observations- looking at damaged brains
• Recording Electrical Activity EEG ( electroencephslogram)
• an amplified recording of the waves of electrical activity that sweep across the brain’s surface
EEG
Tools of Discovery• Neuroimaging-
– CT ( Computed tomography) Scan- • X- Ray photographs
– PET ( Positron emission tomography) Scan• Looks at sugar glucose to determine brain activity
– “HOT SPOTS”
– MRI- ( Magnetic Resonance Imaging) • generated images that distinguish among different types
of soft tissue; allows us to see structures within the brain.
PET Scan
PET Scan
MRI
The Brain
•
Lower Brain
Lower Brain-
• performs life saving operations freeing the higher brain regions to think, dream, memorize..
• We are unaware of most of its functions
Lower Level Brain StructureThe Brainstem
1. Brainstem-• where spinal cord enters the skull• Crossover point for nerves
• responsible for automatic survival functions
2. Medulla- Heartbeat and breathing
Lower Level Brain StructureThe Brainstem3. Reticular Formation-
• Filter and relay station• Controls arousal
4. Thalamus-
• Sensory input station,except smell
• Receives higher brains replies• Controls electrical cycles. Slows
during sleep;speeds up while awake
•
Lower Level Brain StructureThe Brainstem
• 5. The Cerebellum
• Coordinates voluntary movements –Balancing, walking……….
• Nonverbal voluntary movement
• 6. Pons– Regulates sleep
The Limbic System
–associated with emotions such as fear and aggression and drives such as those for food and sex
–includes the hippocampus, amygdala, and hypothalamus.
The Limbic System
• 1. Hippocampus-
• Processes memory
• Forms new memories
• 2. Amygdala-
• Aggression and fear
The Limbic System• 3. Hypothalamus-
– Controls pituitary gland (hormones)
– directs several maintenance activities• eating• drinking• body temperature
– Triggers autonomic nervous system– Pleasure Center– Reward Deficiency Syndrome- alcoholism, binge
drinking, drug abuse
Psychosurgery?
• What is psychosurgery?
The Cerebral Cortex• Thin layer covering your cerebral
hemispheres- wrinkly thing
• Neural cells
• Controls body and info
• The bigger the better
The Cerebral CortexStructure and Functions
1. Each hemisphere is divided up into 4 lobes• Frontal• Occipital• Temporal• Parietal
2. Glial Cells- -
• neural nannies• Support the 22 billion nerve cells
The Cerebral Cortex
1. Frontal Lobe- speaking, muscle movement, making plans, judgments
• Motor Cortex- outgoing messages to the body
The Cerebral Cortex2.Parietal Lobe- sensory cortex
• Sensory Cortex-registers and processes body sensations
• Receives info from skin receptors
• More sensitive= bigger area
3.Occipital Lobe- receives visual from opposite sides
The Cerebral Cortex4.Temporal Lobes- receive auditory
simulation from opposite sides
• Don’t need real sounds
Functional MRI scan of the visual cortex activated by light shown in the subject’s eyes`
Auditorycortex
Visualcortex
The Cerebral Cortex• Association Areas-
areas of the cerebral cortex that are not involved in primary motor or sensory functions
involved in higher mental functions such as learning, remembering, thinking, and speaking
Association Areas• Aphasia
– impairment of language, usually caused by left hemisphere damage either to Broca’s area (impairing speaking) or to Wernicke’s area (impairing understanding)
• Broca’s Area – an area of the left frontal lobe that directs the muscle movements involved in
speech
• Wernicke’s Area – an area of the left temporal lobe involved in language comprehension
• Angular Gyrus-auditory sounds
The Cerebral CortexBrain activity when hearing, seeing, and speaking words
Brain Reorganization
• Plasticity- neural tissue can reorganize in response to damage
•Orgasm in foot
•Most plastic when young
Our Divided Brain• Corpus Callosum
– largest bundle of neural fibers
– connects the two brain hemispheres
– carries messages between the hemispheres
Corpus callosum
Split Brain• a condition in which the two
hemispheres of the brain are isolated by cutting the connecting fibers (mainly those of the corpus callosum) between them
• “alien hand syndrome”
Hemispheric Differences
• Specialization • Each hemisphere has its own
specialties• Most people are stronger in one
hemisphere • Left- logical, verbal, sequential • Right- emotional, expressive, better at
spatial relations
Handedness
• 90% right handed
The percentage of lefties sharplydeclines with age
10 20 30 40 50 60 70 80 90Age in years
14%
12
10
8
6
4
2
0
Percentage ofleft-handedness
Neural and Hormonal Systems
• Endocrine System
– the body’s “slow” chemical communication system
– a set of glands that secrete hormones into the bloodstream
Endocrine System
• Hormones– chemical messengers, mostly those
manufactured by the endocrine glands, that are produced in one tissue and affect another
– Growth, reproduction, metabolism, mood………
Endocrine System• Adrenal Glands
– a pair of endocrine glands just above the kidneys
– secrete the hormones epinephrine (adrenaline) and norepinephrine (noradrenaline), which help to arouse the body in times of stress
– Increases heart beat, blood pressure, blood sugar….. Gives us energy
Endocrine System
• Pituitary Gland– under the influence of the
hypothalamus, the pituitary regulates growth and controls other endocrine glands
– Master gland
Other Hormones /Glands1. Pineal Gland-
• Produces melatonin • regulates circadian rhythms• Seasonal Affective disorder
2. Thyroid- • Maintains metabolic activities• Lack of thyronixe= mental retardation in
children
3. Pancreas- releases insulin and glucagon which regulates blood sugar
Other Hormones /Glands
• 4. Gonads-
–Testis and Ovaries–Release estrogen and
testosterone