OmicsOmics TechnologyTechnology

ByMohammed Z. Naji

Contents Introduction –Introduction –What is OMICS technology?What is OMICS technology? History of Omics History of Omics Omes and Omics Omes and Omics Types of OmicsTypes of Omics

Introduction

The complete sequencing of the The complete sequencing of the human genome has ushered in a human genome has ushered in a new era of systems biology new era of systems biology referred to as referred to as Omics technologyOmics technology. .

Introduction The term ‘‘omic’’ is derived from the

Latin suffix ‘‘ome’’ meaning mass or many. Thus, OMICS involve a mass (large number) of measurements per endpoint.

In biological context , suffix –omics is used to refer to the study of large sets of biological molecules

The term omics refers to the The term omics refers to the comprehensive analysis of comprehensive analysis of biological systemsbiological systems that focuses that focuses on complex systems of life.on complex systems of life.

Omics technology mostly done by

softwares

History of OmicsHistory of OmicsThe first genome was completely sequenced by Sanger in Cambridge, UK, in the 1970s. Genome is the most fundamental part of many omics. The word genomics is said to be appeared in the 1980s and became widely used in the 1990s. 

Omes & Omics

The word The word ’omics’’omics’ refers to a  refers to a field of study field of study in biology ending in biology ending in the suffix in the suffix -omics-omics such as  such as genomics, metabolomics, or genomics, metabolomics, or proteomics. proteomics.

The related The related omeome addresses  addresses the objects of study the objects of study of such of such fields, such as the genome, fields, such as the genome, metabolome, or proteome metabolome, or proteome respectively.respectively.

Main Types of OMICS OMICS technologies :

Genomics Transcriptomics Proteomics Metabolomics

Glycome & Glycomics Immunolome & Immunolomics Lipidome & Lipidomics Lipoproteome & Lipoproteomics Cellome & Cellomics Antibodyome & Antibodyomics Diseaseome & Diseaseomics Epigenome & Epigenomics Foodome &Foodomics

Other Types of OMICS ….

Software of DatabaseSoftware of Database

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((http://www.ebi.ac.uk/fasta33/))

((http://pir.georgetown.edu/pirwww/search/fasta.html))

A BLAST A BLAST ResultResult

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(Radial Tree)(Radial Tree)

(Phylogram)(Phylogram)

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((http://www.sanger.ac.uk/Software/Pfam/search.shtml))

((http://smart.embl-heidelberg.de))

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Human and Mouse TranscriptomeHuman and Mouse Transcriptome ((http://expression.gnf.org/cgi-bin/index.cgi))

((http://genome-www. stanford.edu/serum/))

Do you think the OMICS Do you think the OMICS Techniques reach to the space?Techniques reach to the space?