Biochemistry of Cells 1. Carbon-based Molecules Although a cell is mostly water, the rest of the...

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Biochemistry of Cells

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Carbon-based Molecules

•Although a cell is mostly water, the rest of the cell consists mostly of carbon-based molecules

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Organic chemistry is the study of all compounds that contain C – C bonds

Uses of Organic Molecules•Americans consume an average of 140 pounds of sugar per person per year

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Cellulose, found in plant cell walls, is the most abundant organic compound on Earth

Uses of Organic Molecules• A typical cell in

your body has about 2 meters of DNA

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A typical cow produces over 200 pounds of methane gas each year

Large Hydrocarbons:• Are the main

molecules in the gasoline we burn in our cars

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The hydrocarbons of

fat molecules provide energy for our bodies

Carbon is a Versatile Atom

• Two reasons why carbon is so important:

• 1. It has four electrons in an outer shell - so carbon can share its electrons with 4 OTHER atoms

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2. Carbon can use its bonds to attach to other CARBONS to form an endless

diversity of carbon skeletons

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4 Major Groups of Organic Macromolecules

•Proteins

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Lipids

CarbohydrateNucleic Acids

MACROMOLECULES•“giant” molecules made from joining smaller units together = polymers

•Mono = one

•Poly = many

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Make a chart like this in your notes:

Macromolecule

Examples Monomer Function

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Carbohydrates

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Carbohydrates

•Living things use carbohydrates as their main source of energy.

•Plants and some animals use carbohydrates for structural

purposes.

•Carbohydrates include:• Small sugar molecules•Long starch molecules

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Monosaccharides = 1

•Glucose is found in sports drinks

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Fructose is found in fruitsHoney contains both glucose & fructoseGalactose is called “milk sugar”

Polysaccharides = many

•Complex carbohydrates

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Composed of many sugar monomers linked together

Glycogen• Glycogen is an example

of a polysaccharide in animals

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Animals store excess sugar in the form of glycogen

Cellulose• Cellulose is an

example of a polysaccharide in plants.

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It is a major component of wood

It is also known as dietary fiber

Lipids

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Lipids

• - Include fats, waxes and oils• - Lipids are hydrophobic –”water fearing”

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They do NOT mix with water

FAT MOLECULE

Function of Lipids

- store energy- insulate the body- main component of cell membranes

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Many lipids are fatty acids.

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Nucleic Acids

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Nucleic Acids

•Store hereditary information

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Contain information for making all the body’s proteinsDNA & RNA

Nucleic Acids

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Nitrogenous base(A,G,C, or T)

Phosphategroup

Thymine (T)

Sugar(deoxyribose)

Phosphate

BaseSugar

Monomer: nucleotide

Nucleotide

Proteins

• monomers = amino acids (20 of them)

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Proteins are used by the body in many ways:

•catalysts

•structure (building)

•transport

•contracting (muscles)

Some Types of Proteins

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Structural

Contractile

Transport

Proteins as Enzymes (Catalyst)

• Many proteins act as catalysts or enzymes – they make chemical reactions go faster.

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Thousands of different enzymes exist in the body.

Enzymes fold into specific shapes so that they can “recognize” their substrate.

Chemical reactions involve breaking and reforming bonds

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reactants

substrate

products

Substrates are the reactants that enzymes work on

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Enzymes provide a site where reactants come together to react!

How the Enzyme Works

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Enzyme Key Points:

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• Enzymes make reactions go FASTER

• Enzymes are NOT used up

• Enzymes are SPECIFIC

• Enzymes are sensitive to temperature and pH

Denaturating Proteins

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Changes in temperature & pH can denature (unfold) a protein so it

no longer worksCooking denatures protein in eggs

Milk protein separates into curds & whey when it denatures

Effect of temperature and pH on enzymes

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Summary of Key Concepts

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Macromolecules

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Macromolecules

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Biochemistry Vocabulary

• Organic• macromolecule• carbohydrate• saccharide (mono, di, poly)• protein• amino acid• lipid• nucleic acid• nucleotide

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Organicmacromoleculecarbohydratesaccharide (mono, di, poly)proteinamino acidactive siteenzymesubstratecatalystlipidnucleic acidnucleotide

• active site• enzyme• substrate• catalyst

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