Post on 23-Dec-2015
Automated Insulin Preparation System
Progress ReportGroup 22: Brant Cauthorn, Jessica Filderman, and Kellie StokaClient: Dr. Klaesner
Product Need
Prevalence 366 million people worldwide1
Cost $465 billion a year worldwide1
50% of people inject insulin wrong2
Why people do it wrong: Visual Impairment Peripheral Neuropathy Arthritis
1 Chang, Maria. The Huffington Post, 13 September 2011.2 Wartburg, Linda. Diabetes Health, 21 March 2009.
Design Requirements General:
Small size Inexpensive Can be used in a home
setting Limited complexity
Operation: Safe Accurate Not limited by user health
conditions Room Temperature
Minimum functions: Hold two 10 ml insulin
vial(s) Mix insulin vial(s) Sterilize vial(s) Uncap needles Insert needle into vial(s) Withdraw a specified
amount of insulin
Design Process Optional Features
Injection Capability? Temperature Control? Blood Glucose Monitor? Storage of Vials? Data Communication? Dose Verification?
Required Features User Interface Dose Vessel Mixing Sterilization Setting Dose Power Source
Design Alternatives – Optional Features Injection Capability?
No Temperature Control?
No Blood Glucose
Monitor? No
Storage of Vials? Yes
Data Communication? Yes
Dose Verification? Yes
Design Alternatives – User Interface
Keypad Manual “Keys”
Barcode ScannerExternal
Computer
Voice Recognition
Design Alternatives – User Interface
User Interface Weight Keypad Manual KeysBarcode Scanner
External Computer Speech
Ease of Use 10 8 7 9 10 5 7
Reliability 8 10 10 10 9 8 5
Dose Increment 7 10 6 8 9 10 10
Range of Dose Input 7 10 6 8 9 10 10
Cost 7 7 9 7 5 10 9
Availability 6 8 9 9 10 4 10
Size 5 7 7 9 8 10 9
Total 432 386 430 433 398 418
Design Alternatives - Mixing
Conveyor Belts Drop Down Slot Vortex Vertical Arm Shaker User Mixing Tilt Shaker Horizontal Platform Shaker
Design Alternatives - Mixing
Mixing WeightConveyer
Belts
Drop Down Slot Vortex
Arm Shaking
VerticallyUser
MixingTilting
Platform Shaker
Storage Capability 10 10 0 10 10 0 10 10
Compatability 9 9 10 8 10 10 10 10
Complexity 9 8 10 6 6 10 8 7
Accuracy 7 9 7 7 7 10 8 8
Reliability 7 9 10 7 6 9 9 8
Size 6 8 9 8 6 10 8 7
Cost 6 8 9 8 6 10 8 8
Speed 5 8 9 8 8 10 8 8
Total 515 452 460 447 483 517 495
Design Alternatives - Sterilization
Spray top of vial with isopropyl alcohol Wipe top of vial with isopropyl alcohol pad Dip top of vial in isopropyl alcohol Heat top of vial User sterilizes vial
Sterilization Weight Spraying Wiping Dipping Heat User
Effectiveness 10 9 10 10 8 4
Reliability 10 8 8 8 6 4
Cost 9 9 8 8 8 10
Size 9 9 9 9 9 10
Complexity 8 9 9 7 7 10
Necessary Input? 8 7 6 6 10 10
Total 460 453 437 429 420
Design Alternatives - Sterilization
Design Alternatives - Container
What will hold the insulin? Syringe Insulin Pen Cartridge Catheter
Design Alternatives - Container
Container Weight SyringeInsulin Pen Cartridge Catheter
Cost 8 10 6 9
Pain to User 6 8 10 7
Ease of Use 10 8 9 5
Reliability 8 10 10 7
Sterility 10 10 9 6
Availability 7 10 6 7
Size 5 7 9 8
Portability 6 4 10 0
Total 517 515 369
Design Alternatives - Syringe
Traditional Syringe Significant user difficulty
Modified Syringe Moderate user difficulty
New Syringe Design Minimal user difficulty
???
Design Alternatives - Syringe
New Syringe Design
Design Alternatives - Syringe
Syringe Type Weight Traditional Modified New
Ease of Use 10 5 7 10
Reliability 10 10 10 10
Accuracy 10 10 10 10
Cost 9 10 9 8
Size 8 10 10 10
Total 420 431 452
Design Alternatives – Setting Dose and Drawing Up Insulin Stepper Motor Spacers Bar Pressure
Design Alternatives – Setting Dose and Drawing Up Insulin
Setting Dose Weight Motor Spacers Bar Pressure
Accuracy 10 8 8 8 6
Two types of insulin possible? 10 10 5 10 9
Sterility 9 10 10 10 10
Reliability 8 8 8 8 6
Speed/duration 7 8 6 6 8
Complexity of design 7 8 8 8 6
Cost 6 8 5 6 8
Size 6 10 8 8 8
Total 554 460 516 482
Design Alternatives – Dose Verification Weight
Weigh vials before and after drawing insulin Use density to determine volume change
Light Shine light through syringe, measure absorption Raise light vertically until absorption changes
(Insulin-air interface)
Design Alternatives – Dose Verification
Dose Verification WeightWeight
Solution Light Solution
Compatibility 10 10 9
Reliability 9 5 8
Accuracy 9 8 8
Design complexity 8 8 5
Cost 7 10 9
Size 7 10 9
Total 421 400
Chosen Design
Next Steps
Select materials and parts Determine precise assembly of parts What happens if machine malfunctions Choose convenient locations for supply input Machine waste removal
Schedule
Team Responsibilities
Brant – Website Design and Maintenance, CAD Drawings
Kellie – Material & Manufacturing Requirements, CAD Drawings
Jessica – Risk Analysis, Report Editing
Questions?