Post on 13-Apr-2017
Anti-aging therapies through bio-identical hormonal balancing
Dr. Westin Childswww.restartmed.com
Suzanne Somers anti aging regimen- Growth hormone, thyroid hormone,
estradiol, progesterone, pregnenolone, DHEA, GABA, Cortisol, melatonin
- Notice the trend? ALL hormones! - She also uses: daily supplements/vitamins,
frequently detox’s, specialized diet and exercise routines
Anti-aging is not….Old anti-aging paradigm: - Plastic surgery (face lifts, tummy tucks, etc.)- Expensive laser resurfacing- Getting new joints with orthopedic surgery- Treating aches and pains with medications
Anti-aging is
“The specialty is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases”
My definitionAnti-aging is making lifestyle changes including diet, exercise and the supplementation of bio-identical hormones to natural physiologic levels to influence changes at the cellular level which correspond to improvement in both the phenotype and genotype of the individual.
Anti-aging regimen1.Bio-identical hormone replacement (to
physiologic levels)2.Exercise***3.Diet4.Targeted supplements5.Stress and sleep management
(reversal of chronic diseases with targeted medications may be necessary)
HormonesMost powerful molecules in biologyCritical to life - change your DNAControl metabolism of every cellDetermine gender differencesDetermine energy and moodOptimal levels are essential for health and quality of life
2 MAJOR problems...
All hormones decline with age, stress, toxins and illness!- 10% of people have subclinical
hypothyroidism - Every aging human = somatopause,
menopause/andropause- Stress causes early decline of DHEA and
adrenal function- Environment (xenoestrogens)
Doctors don’t get it“reference range endocrinology”- Normal ranges are NOT optimal
- Include 95% of tested ‘sick’ people- NOT diagnostic ranges
- Doctors assume that all ranges are diagnostic- Male free tesosterone: 35-155 5x- Female free testosterone: 0.0-2.2 Infinite- Free t4 (thyroid): 0.6-1.8 3x- AM serum cortisol: 5-25 5x
DHEA (major precursor)
Progesterone and Estrogen
Common view- Persistence of youthful levels of hormones
would cause more heart attacks and cancer- Loss of hormones is adaptive and helps us
live longer- Fits pharmaceutical agenda: take drugs for
symptoms caused by hormone loss
Against the common view- Aging is a natural self destruct program that kicks in
around age 25 in humans- Obesity, high blood pressure, diabetes, heart attacks,
autoimmune diseases and many cancers increase AFTER menopause/andropause
- Aging and loss of hormones are both natural and bad for you
- Studies of balanced hormone restoration show expected youthful benefits and improvements without proof of harm
Thyroid and cortisol deficiencies(fatigue, depression and pain)
- Thyroid sets metabolism, cortisol delivers fuel
- Thyroid determines metabolism in EVERY tissue
- Lack of either = slow metabolism- BOTH must be optimal for health and quality
of life- Doctors have irrational fear of supplementing
Hypothyroidism- Mental fog, poor concentration, depression- Fatigue, need for excessive sleep- Cold extremities, always feel cold- Aches and pains- Thinning, dry, coarse scalp hair- Weight gain- Constipation- Ankle swelling, puffy face
Diagnosing hypothyroidism1st - Symptoms… 2nd - Basal body temp... 97.8-98.23rd - Labs...
TSH Optimal levels 1-2 mU/l (reference range 0.5-4.5) Free T3 > 3.2 (upper ⅓ of reference range)Free T4 > 1.1 (upper ⅓ of reference range) Reverse T3, thyroglobulin antibodies, thyroid peroxidase
antibodies
Right way to fix it- Use of bio-identical T3/T4 hormonal therapy,
titration to relief of symptoms (NOT the TSH)- Iodine, selenium supplementation- Support adrenal function with supplements
or bio-identical cortisol if necessary- Vitamin C, salt, adaptogens
More than “sex hormones” Estradiol, progesterone, testosterone and DHEA are required for the function, growth and maintenance of ALL tissues in both sexes- Maintain brain function and health- Maintain immune system- Maintain connective tissue: skin, hair, bones, muscle- Improve insulin sensitivity: prevent diabetes, fatty liver- Reduce blood pressure- Prevent heart attacks
Normal progesterone dominance
Perimenopause
Menopause
Women killers and hormones- Cardiovascular disease, osteoporosis, dementia and
breast cancer = RARE before menopause- First 3 = estradiol deficiency, breast cancer =
progesterone deficiency- Early removal of ovaries = increased risk of heart
disease, osteoporosis and dementia- Youthful hormone levels protect women from these
diseases
Coronary artery disease vs. age
Transdermal estradiol prevents heart attacks
Transdermal estradiol prevents heart attacks
Estrogen replacement preventsAlzheimer’s disease
n=5092 women followed over 5 years
Osteoporosis
Osteoporosis- A hormone deficiency disease - the proper
treatment is hormone restoration- Estradiol prevents resorption of bone while
testosterone, DHEA and GH build new bone- Hormone restoration including vitamin D =
increases bone density better than bisphosphonates without side effects
Estradiol restoration- Protects against heart disease, dementia,
osteoporosis- Improves insulin sensitivity - prevents diabetes- Eliminates hot flashes, restores sleep- Restores cognitive function and mood- Maintains thickness, fullness of skin and hair- Maintains pelvic health, helps against incontinence and
bladder infections- Protects aginst colon cancer and macular degeneration
What about breast cancer?- Estradiol stimulates growth of female
organs, maintains female health and quality of life
- Promotes cancer and other disorders if not balanced with progesterone and androgens
Estrogen Dominance- Autoimmune
diseases- Anxiety- Moodiness- PMS- Bloating, fluid
retention- Fibrocystic breasts
- Heavy periods- Endometriosis- Breast cancer- Ovarian cancer- Uterine cancer- Gallstones
Progesterone balances estrogen- Balanced levels of estrogen/progesterone
prevent breast and endometrial cancer
- Progesterone decline = anxiety, depression, irritability, mood swings, insomnia, pain and inflammation (joint, low back, etc.), osteoporosis
Breast cancer rate vs ageLoss of progesterone = higher risk of breast cancer
Who needs progesterone?- Irregular menstrual cycles- No periods - amenorrhea- Heavy bleeding- Fibrocystic breast disease- Endometriosis/adenomyosis- EVERY woman in menopause
Provera is NOT = to progesteroneProvera- Causes birth defects- Depression- Insomnia, irritability- Fluid retention- Worsens lipid profile- Increases risk of heart attacks- Increases stimulation of
breasts- Causes breast cancer
Progesterone- Maintains pregnancy- Improves mood- Improves sleep- Diuretic- Improves cholesterol- No increase in heart attacks- reduces stimulation of
breasts- PREVENTS breast cancer
E3N-EPIC study55,000 women8 year f/u
E2 plus progesterone = no increased risk of breast cancer
Take aways- Bio-identical hormones
- Transdermal (through the skin)- Estradiol/estriol combination- Natural progesterone- Individualized dose titrated by you- NO harm when used correctly, with LOTS of benefit
Take aways- New anti-aging medicine
- Hormones (bio-identical hormones)- Diet- Exercise- Sleep and stress management- Targeted supplements
Questions?