Additional file 2A - C

A Small bowel Large bowelB

d6

d21

d21

MiHAg mismatch

Syngeneiccontrol

MHC major mismatch

MiHAg mismatch

Syngeneiccontrol

MHC major mismatch

CD4+ CD8+

CD8+ CD90.1+CD4+ CD90.1+

CD90.1+

C Donor T cells (day+6)

Cel

l Cou

nt /

10 H

PFs

0

200

400

600MHC maj mismatchMiHAg mismatchSyngeneic ctrl

Smallbowel

Largebowel

Liver Skin

Donor T cells (day+21)

Cel

l Cou

nt /

10 H

PFs

0

200

400

600MiHAg mismatchSyngeneic ctrl

Smallbowel

Largebowel

Liver Skin

*

** Death due to acute GvHD

*

** Death due to acute GvHD