ADC CalculationsADC Calculations

Joshua Kim

I. Objective and GoalsII. Current ADC ResultsIII. Current Progress on MatLab Program

Outline

Objective and Goals

Objective› To calculate ADC values for all patients

Goals› To study the pixel intensity variations with translation.› To calculate the combined effects of image statistical error

with contour placement uncertainty.› To create a MatLab GUI program that can make the ADC

analysis faster.

Current ADC Results (Meyers)ADC Graph

0

0.5

1

1.5

2

2.5

0 520 850

b-value (s/mm^2)

-ln

(Ii/

Io)

Scan 1

Scan 2

Scan 3

Scan 4

b = 0

b = 520

b = 850

MatLab Program

Problem:› Some lesions are very

difficult to contour

› Would like to study lesion pixel variation with translation.

› Also: Want good organization of data and fast analysis

MatLab:› User defined contours for b=0, 520 and 850.› Record coordinates (indices) of contour› Shift in 8 different directions by N pixels› Create ADC value plots as function of shift to study the pixel

variations› Conclude effect of transcription uncertainty

MatLab Program

b = 0 b = 520 b = 850

Future Work

Complete transcription error component of MatLab

Write code for organizing data

Complete ADC calculations for all patients