2014 06 04 - LOINC Introduction - Brief

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Introduction and Overview

Daniel J. Vreeman, PT, DPT, MSc

 Assistant Research Professor 

, Indiana University School of Medicine Associate Director for Terminology Services

, Regenstrief Institute, Inc

© 2014loinc@loinc.org2014.06.04

Laboratory LOINC Workshop - Indianapolis, IN

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loinc.org/slideshows

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Acknowledgements

LOINC Development TeamJami Deckard, Katy Holk, Kelly Malott, DavidBaorto, Clem McDonald

RELMA Development Team

John Hook, Anandhi Sowmyan, James Dennis

LOINC Committee

Sandy Poremba

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Origins of LOINCThe lingua franca of clinical observation exchange

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photo via noshaMcDonald et al. Canopy Computing: using the Web in Clinical Practice. JAMA

. 1998;280(15):1325-1329.

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The rain forest canopy is aseamless web through which

arboreal creatures efficientlymove to reach the edible

fruits without any attentionto the individual trees.

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Arboreal Informatics Pioneers

40 years of EMR work 

Indiana Network for Patient Care 

Regenstrief

– the “Data Switzerland”

Nation’s most comprehensive and longest tenured HIE 

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More than Meets the Eye

photo via chadlewis

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Fundamental challenge: 

Local systems have different ways of

identifying the same concept.

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Only way to corral the

infinite indiosyncracies is

with standards

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A vocabulary standard

would serve as theRosetta Stone.

photo via Hans Hillewaert / CC-BY-SA-3.0

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Logical

Observation

Identifiers

Names and

CodesA universal code system that facilitates exchange,

pooling, and processing of results

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Established in 1994 byRegenstrief Institute. 

Vocabulary standard forobservation identifiers.

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Similar name, different meaning…

photo via Caption Time

i i i i

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Similar name, different meaning…

meerkat meerkat mere cat  meerkat

photo via Caption Time

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MEASUREMENTS US

   “     R   ”

photo via puuikibeach

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If an observation is a question and

the observation value is 

an answer… LOINC provides codes for questions  Where needed, other vocabulariesprovide codes for answers 

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What is my patient’s

hemoglobin level?718-7:Hemoglobin:MCnc:Pt:Bld:Qn

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How fast does my patient

usually walk?41959-8:Walking speed:Vel:1W^mean:^Patient:Qn:Calculated

photo via Ed Yourdon

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Indiana Network for Patient Care

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Indiana Network for Patient Care

di k f i C

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$||||||||

 OBR|1|||012^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|NM|123^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|NM|234^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|NM|345^HGB^HSP_A^718-7^Hemoglobin [Mass/volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|NM|456^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem

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OBX||CE|57131-5^Newborn conditions with pos markers^LN||7573000^PKU^SCT

Result with a Coded Value

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OBX||CE|57131-5^Newborn conditions with pos markers^LN||7573000^PKU^SCT

Result with a Coded Value

Data type of result(OBX-5) is a coded

element

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OBX||CE|57131-5^Newborn conditions with pos markers^LN||7573000^PKU^SCT

Result with a Coded Value

Data type of result(OBX-5) is a coded

element

This code isfrom LOINC

Code identifying thisobservation

(what are these results?Conditions identified by

newborn screening )

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OBX||CE|57131-5^Newborn conditions with pos markers^LN||7573000^PKU^SCT

Result with a Coded Value

Data type of result(OBX-5) is a coded

element

This code isfrom LOINC

Code identifying thisobservation

(what are these results?Conditions identified by

newborn screening )

This code is fromSNOMED

Code identifying the result(Phenylketonuria )

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photo via eye of einstein

A brief aside about terminology…

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LOINC Terminology

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LOINC Terminology

LOINC (noun)

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

[Chief, Head, etc] LOINCer, LOINCologist (noun)

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

[Chief, Head, etc] LOINCer, LOINCologist (noun)

LOINCification (noun)

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

[Chief, Head, etc] LOINCer, LOINCologist (noun)

LOINCification (noun)

SNOMED Terminology

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

[Chief, Head, etc] LOINCer, LOINCologist (noun)

LOINCification (noun)

SNOMED Terminology

SNOMED (noun)

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

[Chief, Head, etc] LOINCer, LOINCologist (noun)

LOINCification (noun)

SNOMED Terminology

SNOMED (noun)

SNOMEDicated???

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LOINC Terminology

LOINC (noun) To LOINC, LOINCing, LOINCed (verb)

[Chief, Head, etc] LOINCer, LOINCologist (noun)

LOINCification (noun)

SNOMED Terminology

SNOMED (noun)

SNOMEDicated???

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photo via Ludovic Hirlimann

Different standards for differentparts of the elephant.

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We now return to your

regularly scheduledprogram…

photo via x-ray delta one

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Laboratory LOINC

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Clinical LOINC

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Laboratory LOINC Committee Chair:

Clem McDonald, MD 

Clinical LOINC Committee Chair: 

Stan Huff, MD

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LOINC CollectionsPanels, forms, surveys, and other patientassessments

photo via LuzA

Standardized Assessments and Collections

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Vreeman DJ, McDonald CJ, Huff SM. Representing patient assessments in LOINC®. AMIA Ann u Symp Proc. 2010;832-836. PMID: 21347095 . Vreeman DJ, McDonald CJ, Huff SM. LOINC® - A Universal Catalog o f Individual Clinical Observations and Uniform Representation of Enum erated Collections. Int J Funct Inform

Personal Med. 2010;3(4):273-291.

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The LOINC ApproachOpen. Nimble. Pragmatic.

Open Development

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Open Development

Worldwide distribution at no cost 

New terms from end-users 

Welcome all comers Committees are volunteers

Open Development

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Open Development

Worldwide distribution at no cost 

New terms from end-users 

Welcome all comers Committees are volunteers

Open Development

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Open Development

Worldwide distribution at no cost 

New terms from end-users 

Welcome all comers Committees are volunteers

It’s free, but invaluable 

R i f I i

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Regenstrief Institute

Steward 

Developer of content 

Developer of tools 

Developer of community 

Distributor 

Voice

F di S

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Funding Support

Main current sources are: 

U.S. National Library of MedicineRegenstrief Foundation 

Prior support from 

Several other U.S. federal agenciesJohn A. Hartford Foundation

LOINC Codes Over Time by Release

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1

2

3

4

5

6

7

8

  4   /   2  4

   /   1   9   9

   5     |     1 .   0

   5   /   2  4

   /   1   9   9

   5     |     1 .   0  a

  6   /   2   3

   /   1   9   9

   5     |     1 .   0    b

  6   /   2   8

   /   1   9   9

   5     |     1 .   0  c 

    7   /   1  4

   /   1   9   9

   5     |     1 .   0  d

   9   /   1   5

   /   1   9   9

   5     |     1 .   0  e

   1   2   /   2

   1   /   1   9

   9   5     |     1 .   0   f

  4   /   2   8

   /   1   9   9

  6     |     1 .   0  g 

   8   /   2

   9   /   1   9

   9  6     |     1 .   0    h

   (    2    )

   1   2   /

   3   /   1   9

   9  6     |     1 .   0    h

   (    3    )

   1   /   8   /

   1   9   9   9

    7     |     1 .   0    i

   1   0   /   9

   /   1   9   9

    7     |     1 .   0    j   -  a

   5   /   1   /

   1   9   9   8

     |     1 .   0    k

   2   /   1   2

   /   1   9   9

   9     |     1 .   0    l

    7   /   2   3

   /   1   9   9

   9     |     1 .   0   m

   8   /  6   /

   1   9   9   9

     |     1 .   0   m  a

   2   /  4   /

   2   0   0   0

     |     1 .   0   n 

  6   /   1   3

   /   2   0   0

   0     |     1 .   0   0

   1   /   1   /

   2   0   0   1

     |     2 .   0   0

   1   /   3   1

   /   2   0   0

   1     |     2 .   0   1

    7   /   1   /

   2   0   0   1

     |     2 .   0   3

   1   /   1   /

   2   0   0   2

     |     2 .   0  4

   2   /   1   /

   2   0   0   2

     |     2 .   0   5

   2   /   1   9

   /   2   0   0

   2     |     2 .   0  6

   8   /   1   /

   2   0   0   2

     |     2 .   0    7

   9   /   1   /

   2   0   0   2

     |     2 .   0   8

   5   /   1   /

   2   0   0   3

     |     2 .   0   9

   1   0   /   1

   /   2   0   0

   3     |     2 .   1   0

   1   /   1   /

   2   0   0  4

     |     2 .   1   1

   2   /   1   /

   2   0   0  4

     |     2 .   1   2

   1   2   /   1

   /   2   0   0

  4     |     2 .   1   3

   1   2   /   1

   /   2   0   0

  4     |     2 .   1  4

  6   /   1   /

   2   0   0   5

     |     2 .   1   5

   1   2   /   1

   /   2   0   0

   5     |     2 .   1  6

  6   /   1   /

   2   0   0  6

     |     2 .   1    7

   1   2   /   2

   1   /   2   0

   0  6    |    2 .   1   9

  6   /   2   1

   /   2   0   0

    7    |    2 .   2   1

   1   2   /   0

   3   /   2   0

   0    7    |    2 .   2   2

    7   /   1   0

   /   2   0   0

   8    |    2 .   2  4

   1   /   1   0

   /   2   0   0

   9    |    2 .   2  6

   0    7   /   0

  6   /   2   0

   0   9    |    2 .   2    7

   1   2   /   3

   0   /   2   0

   0   9    |    2 .   2   9

   2   /   2  6

   /   2   0   1

   0    |    2 .   3   0

  6   /   1   5

   /   2   0   1

   0    |    2 .   3   2

   1   2   /   2

   9   /   2   0

   1   0    |    2 .   3  4

   0  6   /   3

   0   /   2   0

   1   1    |    2 .   3  6

   1   2   /   3

   0   /   2   0

   1   1    |    2 .   3   8

  6   /   3   0

   /   2   0   1

   2    |    2 .  4   0

   1   2   /   3

   0   /   2   0

   1   2    |    2 .  4

   2

   0  6   /   2

   9   /   2   0

   1   3    |    2 .  4

  4

   1   2   /   2

  6   /   2   0

   1   3    |    2 .  4

  6

LOINC Codes

Only Lab LOINC Codes

y

laboratory terms only

LOINC Codes Over Time by Release

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1

2

3

4

5

6

7

8

  4   /   2  4

   /   1   9   9

   5     |     1 .   0

   5   /   2  4

   /   1   9   9

   5     |     1 .   0  a

  6   /   2   3

   /   1   9   9

   5     |     1 .   0    b

  6   /   2   8

   /   1   9   9

   5     |     1 .   0  c 

    7   /   1  4

   /   1   9   9

   5     |     1 .   0  d

   9   /   1   5

   /   1   9   9

   5     |     1 .   0  e

   1   2   /   2

   1   /   1   9

   9   5     |     1 .   0   f

  4   /   2   8

   /   1   9   9

  6     |     1 .   0  g 

   8   /   2

   9   /   1   9

   9  6     |     1 .   0    h

   (    2    )

   1   2   /

   3   /   1   9

   9  6     |     1 .   0    h

   (    3    )

   1   /   8   /

   1   9   9   9

    7     |     1 .   0    i

   1   0   /   9

   /   1   9   9

    7     |     1 .   0    j   -  a

   5   /   1   /

   1   9   9   8

     |     1 .   0    k

   2   /   1   2

   /   1   9   9

   9     |     1 .   0    l

    7   /   2   3

   /   1   9   9

   9     |     1 .   0   m

   8   /  6   /

   1   9   9   9

     |     1 .   0   m  a

   2   /  4   /

   2   0   0   0

     |     1 .   0   n 

  6   /   1   3

   /   2   0   0

   0     |     1 .   0   0

   1   /   1   /

   2   0   0   1

     |     2 .   0   0

   1   /   3   1

   /   2   0   0

   1     |     2 .   0   1

    7   /   1   /

   2   0   0   1

     |     2 .   0   3

   1   /   1   /

   2   0   0   2

     |     2 .   0  4

   2   /   1   /

   2   0   0   2

     |     2 .   0   5

   2   /   1   9

   /   2   0   0

   2     |     2 .   0  6

   8   /   1   /

   2   0   0   2

     |     2 .   0    7

   9   /   1   /

   2   0   0   2

     |     2 .   0   8

   5   /   1   /

   2   0   0   3

     |     2 .   0   9

   1   0   /   1

   /   2   0   0

   3     |     2 .   1   0

   1   /   1   /

   2   0   0  4

     |     2 .   1   1

   2   /   1   /

   2   0   0  4

     |     2 .   1   2

   1   2   /   1

   /   2   0   0

  4     |     2 .   1   3

   1   2   /   1

   /   2   0   0

  4     |     2 .   1  4

  6   /   1   /

   2   0   0   5

     |     2 .   1   5

   1   2   /   1

   /   2   0   0

   5     |     2 .   1  6

  6   /   1   /

   2   0   0  6

     |     2 .   1    7

   1   2   /   2

   1   /   2   0

   0  6    |    2 .   1   9

  6   /   2   1

   /   2   0   0

    7    |    2 .   2   1

   1   2   /   0

   3   /   2   0

   0    7    |    2 .   2   2

    7   /   1   0

   /   2   0   0

   8    |    2 .   2  4

   1   /   1   0

   /   2   0   0

   9    |    2 .   2  6

   0    7   /   0

  6   /   2   0

   0   9    |    2 .   2    7

   1   2   /   3

   0   /   2   0

   0   9    |    2 .   2   9

   2   /   2  6

   /   2   0   1

   0    |    2 .   3   0

  6   /   1   5

   /   2   0   1

   0    |    2 .   3   2

   1   2   /   2

   9   /   2   0

   1   0    |    2 .   3  4

   0  6   /   3

   0   /   2   0

   1   1    |    2 .   3  6

   1   2   /   3

   0   /   2   0

   1   1    |    2 .   3   8

  6   /   3   0

   /   2   0   1

   2    |    2 .  4   0

   1   2   /   3

   0   /   2   0

   1   2    |    2 .  4

   2

   0  6   /   2

   9   /   2   0

   1   3    |    2 .  4

  4

   1   2   /   2

  6   /   2   0

   1   3    |    2 .  4

  6

LOINC Codes

Only Lab LOINC Codes

y

Slope = 600

laboratory terms only

LOINC Codes Over Time by Release

8/12/2019 2014 06 04 - LOINC Introduction - Brief

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1

2

3

4

5

6

7

8

  4   /   2  4

   /   1   9   9

   5     |     1 .   0

   5   /   2  4

   /   1   9   9

   5     |     1 .   0  a

  6   /   2   3

   /   1   9   9

   5     |     1 .   0    b

  6   /   2   8

   /   1   9   9

   5     |     1 .   0  c 

    7   /   1  4

   /   1   9   9

   5     |     1 .   0  d

   9   /   1   5

   /   1   9   9

   5     |     1 .   0  e

   1   2   /   2

   1   /   1   9

   9   5     |     1 .   0   f

  4   /   2   8

   /   1   9   9

  6     |     1 .   0  g 

   8   /   2

   9   /   1   9

   9  6     |     1 .   0    h

   (    2    )

   1   2   /

   3   /   1   9

   9  6     |     1 .   0    h

   (    3    )

   1   /   8   /

   1   9   9   9

    7     |     1 .   0    i

   1   0   /   9

   /   1   9   9

    7     |     1 .   0    j   -  a

   5   /   1   /

   1   9   9   8

     |     1 .   0    k

   2   /   1   2

   /   1   9   9

   9     |     1 .   0    l

    7   /   2   3

   /   1   9   9

   9     |     1 .   0   m

   8   /  6   /

   1   9   9   9

     |     1 .   0   m  a

   2   /  4   /

   2   0   0   0

     |     1 .   0   n 

  6   /   1   3

   /   2   0   0

   0     |     1 .   0   0

   1   /   1   /

   2   0   0   1

     |     2 .   0   0

   1   /   3   1

   /   2   0   0

   1     |     2 .   0   1

    7   /   1   /

   2   0   0   1

     |     2 .   0   3

   1   /   1   /

   2   0   0   2

     |     2 .   0  4

   2   /   1   /

   2   0   0   2

     |     2 .   0   5

   2   /   1   9

   /   2   0   0

   2     |     2 .   0  6

   8   /   1   /

   2   0   0   2

     |     2 .   0    7

   9   /   1   /

   2   0   0   2

     |     2 .   0   8

   5   /   1   /

   2   0   0   3

     |     2 .   0   9

   1   0   /   1

   /   2   0   0

   3     |     2 .   1   0

   1   /   1   /

   2   0   0  4

     |     2 .   1   1

   2   /   1   /

   2   0   0  4

     |     2 .   1   2

   1   2   /   1

   /   2   0   0

  4     |     2 .   1   3

   1   2   /   1

   /   2   0   0

  4     |     2 .   1  4

  6   /   1   /

   2   0   0   5

     |     2 .   1   5

   1   2   /   1

   /   2   0   0

   5     |     2 .   1  6

  6   /   1   /

   2   0   0  6

     |     2 .   1    7

   1   2   /   2

   1   /   2   0

   0  6    |    2 .   1   9

  6   /   2   1

   /   2   0   0

    7    |    2 .   2   1

   1   2   /   0

   3   /   2   0

   0    7    |    2 .   2   2

    7   /   1   0

   /   2   0   0

   8    |    2 .   2  4

   1   /   1   0

   /   2   0   0

   9    |    2 .   2  6

   0    7   /   0

  6   /   2   0

   0   9    |    2 .   2    7

   1   2   /   3

   0   /   2   0

   0   9    |    2 .   2   9

   2   /   2  6

   /   2   0   1

   0    |    2 .   3   0

  6   /   1   5

   /   2   0   1

   0    |    2 .   3   2

   1   2   /   2

   9   /   2   0

   1   0    |    2 .   3  4

   0  6   /   3

   0   /   2   0

   1   1    |    2 .   3  6

   1   2   /   3

   0   /   2   0

   1   1    |    2 .   3   8

  6   /   3   0

   /   2   0   1

   2    |    2 .  4   0

   1   2   /   3

   0   /   2   0

   1   2    |    2 .  4

   2

   0  6   /   2

   9   /   2   0

   1   3    |    2 .  4

  4

   1   2   /   2

  6   /   2   0

   1   3    |    2 .  4

  6

LOINC Codes

Only Lab LOINC Codes

y

Slope = 600

Slope = 2200

laboratory terms only

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Lots Cooking…Always more lab tests

Genetic reporting

Lots of survey instruments, forms, and assessments

More radiology reportsStructured document titles

photo via liber

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32,000+ users in 162 countries

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32,000 users in 162 countries

loinc.org registered users

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0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

 6 /  1 /  0  8

  1  2 /  1 /  0  8

 6 /  1 /  0  9

  1  2 /  1 /  0  9

 6 /  1 /  1  0

  1  2 /  1 /  1  0

 6 /  1 /  1  1

  1  2 /  1 /  1  1

 6 /  1 /  1  2

  1  2 /  1 /  1  2

 6 /  1 /  1  3

  1  2 /  1 /  1  3

g g

loinc.org registered users

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0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

 6 /  1 /  0  8

  1  2 /  1 /  0  8

 6 /  1 /  0  9

  1  2 /  1 /  0  9

 6 /  1 /  1  0

  1  2 /  1 /  1  0

 6 /  1 /  1  1

  1  2 /  1 /  1  1

 6 /  1 /  1  2

  1  2 /  1 /  1  2

 6 /  1 /  1  3

  1  2 /  1 /  1  3

g g

725 new users per month8,700 new users per year

loinc.org registered users

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0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

 6 /  1 /  0  8

  1  2 /  1 /  0  8

 6 /  1 /  0  9

  1  2 /  1 /  0  9

 6 /  1 /  1  0

  1  2 /  1 /  1  0

 6 /  1 /  1  1

  1  2 /  1 /  1  1

 6 /  1 /  1  2

  1  2 /  1 /  1  2

 6 /  1 /  1  3

  1  2 /  1 /  1  3

g g

725 new users per month8,700 new users per year

 Doubled in 19 months!

loinc.org registered users

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0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

 6 /  1 /  0  8

  1  2 /  1 /  0  8

 6 /  1 /  0  9

  1  2 /  1 /  0  9

 6 /  1 /  1  0

  1  2 /  1 /  1  0

 6 /  1 /  1  1

  1  2 /  1 /  1  1

 6 /  1 /  1  2

  1  2 /  1 /  1  2

 6 /  1 /  1  3

  1  2 /  1 /  1  3

725 new users per month8,700 new users per year

Ave growth/mo:

2009 = 2762010 = 307

2011 = 3792012 = 5002013 = 667

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Tools forImplementers

photo via Robert S Donovan

loinc.org/downloads

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loinc.org/downloads

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d wnl ad 1400/ nth

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loinc.org/get-started

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g g

search.loinc.org

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g

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Alternate Language Search

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Alternate Language Search

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 Everything in Italian!

loinc.org/mailing-lists

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N ! N l tloinc.org/mailing-lists

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No spam! News + release notices

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@LOINC

loinc.org/slideshows

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loinc.org/adopters

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loinc.org/adopters

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List your organization. Free!

forum.loinc.org

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loinc.org/usage

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loinc.org/usage

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loinc.org/usage

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loinc.org/usage

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loinc.org/usage

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Wisdom of the HerdCan it help novice LOINCers?

photo via suffolktouristguide.com

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photo via jdhancock

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Fidahussein M, Vreeman DJ. A corpus-based approach for automated LOINC mapping. J Am Med Inform Assoc. 2013 May 15. [Epub ahead of print] PubMed PMID: 23676247.

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Maxent vs Lucene

Mapping Performance on 3 INPC LabsC 101 d t with b t 80 00 l l t

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Corpus = 101 code sets with about 80,00 local terms

Mapping Performance on 3 INPC LabsC r 101 de et with ab t 80 00 l al ter

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~79% = Not bad!

Corpus = 101 code sets with about 80,00 local terms

57%

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57% of local lab codes would always have

the correct LOINC ranked first byusing a Maxent cutoff of 0.46

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Connecting RELMA to acommunity repository

of LOINC MappingsDaniel J. Vreeman, PT, DPT, MSc

Masoud Hosseini, MS

John HookAnandhi Sowmyan

James Dennis

Brian E. Dixon, MPA, PhD, FHIMSS

photo via jamescridland

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RELMA®REgenstrief LOINC Mapping Assistant

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22 organizations, 5 countries, 102,000 mappings

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# of codes and institutions mapped to this LOINC 

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# of codes and institutions mapped to this LOINC 

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# of codes and institutions mapped to this LOINC 

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Click here to see the local codes!

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When you’ve got a decent number of mappings,share them back with the community

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share them back with the community

When you’ve got a decent number of mappings,share them back with the community

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share them back with the community

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LOINC PremiumMembership Programmembers.loinc.org

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What’s still free?

All the Usual Awesomeness

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LOINC Table

Accessory Files

RELMA Program

DocumentationWeb search app (search.loinc.org)

Participation in the LOINC Community

Access to submit new concepts to LOINC

Share the love.

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Donate to LOINC.members.loinc.org/donate 

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loinc.org/terms-of-use

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photo via 917press

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Just kidding.

Copyright is a good  thing for

standards. It’s the licensing part that isinteresting.

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No cost 

Worldwide 

In perpetuity

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Use 

Copy 

Distribute

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Any purpose: 

commercial 

non-commercialphoto via Refracted Moments™

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CANNOT use anyLicensed Material to

develop or promulgate adifferent standard for

orders or observations.

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That would defeat

the purpose ofhaving a standard!

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International Adoptionparticipation, translation, implementation 

LOINC Submitters

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Si 2009 150 i ti

LOINC Translators

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22 organizations.

C ntly t n l ti n int 18 i nt f 11 l n

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Vreeman DJ, Chiaravalloti MT, Hook J, McDonald CJ. Enabling international adoption of LOINC through translation. J Biomed Inform.

2012 Aug;45(4):667-73. PMID: 22285984.

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Vreeman DJ, Chiaravalloti MT, Hook J, McDonald CJ. Enabling international adoption of LOINC through translation. J Biomed Inform.

2012 Aug;45(4):667-73. PMID: 22285984.

1st  International

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Vreeman DJ, Chiaravalloti MT, Hook J, McDonald CJ. Enabling international adoption of LOINC through translation. J Biomed Inform.

2012 Aug;45(4):667-73. PMID: 22285984.

1  International LOINC PhD student 

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Adopted as National Standard

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Australia

Austria

Belgium

Brazil

Canada

Cyprus

Estonia

Finland

France

Germany

Iceland

India

Mexico

Mongolia

The Netherlands

New Zealand

Philippines

Portugal

Rwanda

Slovakia

Slovenia

Spain

Thailand

Turkey

United States

Large Implementations

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SIGA Saúde project

7+ Provincial systems in Canada

8+ Regional Health Information Exchanges in Spain

ePSOS

Assistance publique - Hôpitaux de Paris

Hong Kong Hospital Authority

Philippine Health Insurance Corporation

InFSE Project in 5 regions in Italy (LOINC Italia)

Many more...

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For the last few years the AP-HP has

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For the last few years, the AP-HP has

been using the LOINC internationalnomenclature… 

Thanks to this catalogue, the AP-HP isable to use the nomenclature in its

treatment processes, whenever

biology analyses and test results arerequested.

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Vandenbussche PY, Cormont S, André C, et al. Implementation and management of a biomedical observation dictionary in a large healthcare information system.

J Am Med Inform Assoc. 2013 May 1. PMID: 23635601.

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Vandenbussche PY, Cormont S, André C, et al. Implementation and management of a biomedical observation dictionary in a large healthcare information system.

J Am Med Inform Assoc. 2013 May 1. PMID: 23635601.

The results of our workvalidate the choice made to

develop a local dictionaryaligned with LOINC.

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Vandenbussche PY, Cormont S, André C, et al. Implementation and management of a biomedical observation dictionary in a large healthcare information system.

J Am Med Inform Assoc. 2013 May 1. PMID: 23635601.

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Members of the Korean National StandardsCommittee have enthusiastically embraced LOINC 

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Some serious LOINCing in Hong Kong

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S t LOINC

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 Talking about LOINC at the Thai Ministry of

I f t d C t T h l

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D C l d LOINC C

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US AdoptionA few key highlights

Some Key US Adoptions

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All the “big” labs 

All health-related federal agencies

Lots of care organizations 

HIE’s 

Insurance companies 

EHR vendors 

Instrument manufacturers (nascent)

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In USA, major driver ofeHealth standards adoption is EHR Incentive Program 

a.k.a. “Meaningful Use” 

Blumenthal D, Tavenner M. The "meaningful use" regulation for electronic health records. N Engl J Med. 2010 Aug 5;363(6):501-4. Epub 2010 Jul 13. PubMed PMID: 20647183.

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Stage 12011-2012

Data capture

and sharing

Stage 22014

Advance clinical

processes

Stage 32016

Improved care

outcomes

progressive requirements for data standards

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Stage 2starting 2014

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LOINC adopted for: 

1. View, download, transmit data to third party 

2.Cancer case reporting to state registry 

3.Send/receive electronic lab results inambulatory settings 

4.Provide a care summary at care transition 

5.Provide clinical summaries for patients 

6.Submit reportable lab results to public health

Lab reporting to EHRs

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Use in Quality Measures

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LOINC Adopted ForP ti t Ch t i ti

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Patient Characteristics

[Non-lab] Diagnostics studies

Patient experience

Family history

Functional status

Health record component

Interventions (that produce an assessment or measured results)

Laboratory tests

Physical exam

Patient preference

Risk evaluation

System resources (healthcare resources)

An Example Quality MeasureN ti l C itt f Q lit A

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National Committee for Quality Assurance

Diabetes: Hemoglobin A1c

Poor ControlPercentage of patients 18-75 years of age with diabetes who had

hemoglobin A1c > 9.0% during the measurement period.

Find HbA1c in the EHR with LOINC

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Everyone loves LOINC

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photo via mccaughan

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Key Lessons for Today

photo via IMLS DCC

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Not just an I.T. problem

If Murky, Don’t Assume

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Units of measure are critical. 

Sample results can help identify thecorrect LOINC Scale. 

Local experts, package inserts can bevery informative.

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photo via Fishking_1

Upstream standardization.

Ask instrument or test kitmanufacturers.

ivdconnectivity.org

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A journey.

Not a destination.

Ongoing Journey

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Plan for updating as your testing

changes  (less common), or your localcode identifiers change (more common). 

Prioritization

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Local or national policies may helpprioritize mapping subsets. 

For example: 

common results 

+ panel elements 

+ public health reportable testsVreeman DJ, Finnell JT, Overhage JM. A rationale for parsimonious laboratory term mapping by frequency.

 AMIA Annu Symp Proc. 2007 Oct 11:771-5. PubMed PMID: 18693941.

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Need to be mindful ofSecondary Data Usespublic health reporting | electronic quality measures

photo via pagedooley

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Wu J, Finnell JT, Vreeman DJ. Evaluating Congruence Between Laboratory LOINC Value Sets for Quality Measures, Public Health Reporting, and Mapping Common Tests. AMIA Annu Symp Proc. 2013; 1525-1532.

n=2852

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n=2852

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LOINC Top 2000 Results + LOINC Top 300 Orders +

NCD 1 VSAC Q l t LOINC

In closing...

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photo via janeandd

Glad you’re here to at leastget your feet wet

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photo via gmayster01 on & off ...

get your feet wet...

Jump In!

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photo via Justin Ornellas

The Race is On!

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Happy LOINCing!photo via ryarwood

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