ENGR / BRAE 213:Bioengineering Fundamentals

Spring 2015

James Eason (jceason@calpoly.edu)

BRAE 213 students● You have been automatically enrolled in the ENGR 213 PolyLearn page.

● This course will be run from the ENGR 213 page, but you will still get your grade for BRAE 213.

Course Syllabus● Course Description: The purpose of this course is to develop students’ appreciation for the biological sciences and the interplay between biology and engineering. When possible, we will revisit parts of the material that may be covered in BIO 213. We will also be using some simple tools and techniques common to all engineering disciplines

Course Syllabus● Office: 92M-B103

● Office hours: M,W from 2:30-3:45 pm or by appointment

● Email: jceason@calpoly.edu

Policies● You are responsible for all material covered in

lecture, notes, and HW.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.● If you have questions, please contact your instructor

before the due date.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.● If you have questions, please contact your instructor

before the due date.● Late assignments will not be accepted.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.● If you have questions, please contact your instructor

before the due date.● Late assignments will not be accepted.● Don’t cheat or plagiarize, always cite references.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.● If you have questions, please contact your instructor

before the due date.● Late assignments will not be accepted.● Don’t cheat or plagiarize, always cite references.● Scholarly articles or reputable media are preferable.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.● If you have questions, please contact your instructor

before the due date.● Late assignments will not be accepted.● Don’t cheat or plagiarize, always cite references.● Scholarly articles or reputable media are preferable.● Wikipedia is not an acceptable reference.

Policies● You are responsible for all material covered in

lecture, notes, and HW.● It is up to you to make sure HW is submitted

successfully and on time to PolyLearn.● Network or computer problems are not an excuse.● If you have questions, please contact your instructor

before the due date.● Late assignments will not be accepted.● Don’t cheat or plagiarize, always cite references.● Scholarly articles or reputable media are preferable.● Wikipedia is not an acceptable reference.● If you work with another student on an assignment,

make that clear on your submission. Do not submit two copies of the exact same file.

Policies● A course schedule is available in PolyLearn● Consult this schedule regularly for:

● Pre-lecture activities● Lecture notes● HW assignments and deadlines● Grades

Grading and Final Exam

● 10 HW assignments● Final exam

● Date of exam is TBD● Best 10 of 11 grades (10% each)● Complete all HW assignments with 90% average and

you may skip the exam and still get an A.● If you miss one HW assignment, replace it with exam

grade.

Instructor Information

● James Eason

● BS in Electrical Engineering, NC State Univ.

● PhD in Biomedical Engineering, Duke Univ.

● 6 years research

● 12 years teaching

● 3rd year at Cal Poly

Research Interests● Cardiac electrophysiology and arrhythmias

Cardiovascular Disease● The leading cause of death for men & women

● Accounts for one quarter of the deaths in the United States each year (600,000+)

● Care costs over $300 billion/ year (2% of GDP)

● Half of CV-related. deaths are due to coronary artery disease (CAD)

● In the time it takes you to read this slide, there has been one more heart attack in the U.S.

Cardiac arrhythmias:● Lead to most CV-related deaths by way of a lethal

arrhythmia (Sudden Cardiac Death)

● Cause 850,000 hospitalizations per year

● 6 million in U.S. have atrial arrhythmias (2%)

● 25% of people will have atrial arrhythmia in their lifetime

Bioengineering/Biomedical Engineering

● Advances knowledge in engineering, biology, and medicine

● Improves human health through cross-disciplinary activities

● Integrates the engineering sciences with the biomedical sciences and clinical practice.

Examples of Bioengineering work:

• designing and constructing cardiac pacemakers, defibrillators, artificial kidneys, blood oxygenators, hearts, blood vessels, joints, arms, and legs.

• designing computer systems to monitor patients during surgery or to monitor healthy persons in unusual environments (e.g., astronauts in space or underwater divers at great depth).

Examples of Bioengineering work:

• designing and building sensors to measure blood chemistry, such as potassium, sodium, 02, CO2, and pH.

• designing instruments and devices for therapeutic uses, such as a laser system for eye surgery or a device for automated delivery of insulin.

Career Paths

● Bioinstrumentation● Biomechanics● Biomaterials● Systems Physiology● Clinical Engineering● Rehabilitation Engineering● Bioinformatics● Biotechnology

Employment

● Fastest growing field of engineering (27% according to Bureau of Labor Statistics)

● Median salary $87K● California is home to many Biotech companies (36% of extensive list of companies worldwide)

HW Assignment

● Read syllabus● Complete online quiz