Genetic Mutations Accelerated Biology. What is a Mutation? A mutation is a permanent change in the...

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Genetic MutationsAccelerated Biology

What is a Mutation?

A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the protein.

Some causes of mutations include: Radiation, carcinogens, and ultraviolet light.

What is a Deletion Mutation?

A mutation in which one or more bases are omitted from the strand.

Example:Regular sentence: Pet the bad cat

With a deletion mutation:1. Ptt heb adc at (e is deleted)2. Pet the cat (if three are deleted)

What is an Addition Mutation?

A mutation in which one or more bases are added.

Example:Regular sentence: Pet the bad cat

With an addition mutation:1. Pae tth eba dca t

What is a Frameshift Mutation?

When one or two bases are left out or added, and all of the codons after the mutation are now different. If 3 are bases are deleted or added, NO frame shift will occur.

Example:Regular sentence: Pet the bad cat

With a frameshift mutation:1. Ptt heb adc at2. Pet tth eba dca t

What is a Substitution Mutation?

A mutation in which one base is put in the strand in place of another

Example:Regular sentence: Pet the bad cat

With a substitution mutation:Put the bad cat

Usually NOT a frame shift mutation because there are still three codons in the base. Only one is messed up.

Types of Mutations